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Targeting STAT3 by HO3867 induces apoptosis in ovarian clear cell carcinoma.
Bixel K, Saini U, Kumar Bid H, Fowler J, Riley M, Wanner R, Deepa Priya Dorayappan K, Rajendran S, Konishi I, Matsumura N, Cohn DE, Selvendiran K. Bixel K, et al. Int J Cancer. 2017 Nov 1;141(9):1856-1866. doi: 10.1002/ijc.30847. Epub 2017 Jul 24. Int J Cancer. 2017. PMID: 28646535 Free PMC article.
HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer.
Rath KS, Naidu SK, Lata P, Bid HK, Rivera BK, McCann GA, Tierney BJ, Elnaggar AC, Bravo V, Leone G, Houghton P, Hideg K, Kuppusamy P, Cohn DE, Selvendiran K. Rath KS, et al. Cancer Res. 2014 Apr 15;74(8):2316-27. doi: 10.1158/0008-5472.CAN-13-2433. Epub 2014 Mar 3. Cancer Res. 2014. PMID: 24590057 Free PMC article.
A Microfluidic Chip Enables Isolation of Exosomes and Establishment of Their Protein Profiles and Associated Signaling Pathways in Ovarian Cancer.
Dorayappan KDP, Gardner ML, Hisey CL, Zingarelli RA, Smith BQ, Lightfoot MDS, Gogna R, Flannery MM, Hays J, Hansford DJ, Freitas MA, Yu L, Cohn DE, Selvendiran K. Dorayappan KDP, et al. Cancer Res. 2019 Jul 1;79(13):3503-3513. doi: 10.1158/0008-5472.CAN-18-3538. Epub 2019 May 16. Cancer Res. 2019. PMID: 31097475 Free PMC article.