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2009 2
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43 results

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Page 1
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia.
Metallo CM, Gameiro PA, Bell EL, Mattaini KR, Yang J, Hiller K, Jewell CM, Johnson ZR, Irvine DJ, Guarente L, Kelleher JK, Vander Heiden MG, Iliopoulos O, Stephanopoulos G. Metallo CM, et al. Nature. 2011 Nov 20;481(7381):380-4. doi: 10.1038/nature10602. Nature. 2011. PMID: 22101433 Free PMC article.
Isotope tracing in health and disease.
Dong W, Rawat ES, Stephanopoulos G, Abu-Remaileh M. Dong W, et al. Curr Opin Biotechnol. 2022 Aug;76:102739. doi: 10.1016/j.copbio.2022.102739. Epub 2022 Jun 20. Curr Opin Biotechnol. 2022. PMID: 35738210 Free PMC article. Review.
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
Anastasiou D, Yu Y, Israelsen WJ, Jiang JK, Boxer MB, Hong BS, Tempel W, Dimov S, Shen M, Jha A, Yang H, Mattaini KR, Metallo CM, Fiske BP, Courtney KD, Malstrom S, Khan TM, Kung C, Skoumbourdis AP, Veith H, Southall N, Walsh MJ, Brimacombe KR, Leister W, Lunt SY, Johnson ZR, Yen KE, Kunii K, Davidson SM, Christofk HR, Austin CP, Inglese J, Harris MH, Asara JM, Stephanopoulos G, Salituro FG, Jin S, Dang L, Auld DS, Park HW, Cantley LC, Thomas CJ, Vander Heiden MG. Anastasiou D, et al. Nat Chem Biol. 2012 Oct;8(10):839-47. doi: 10.1038/nchembio.1060. Nat Chem Biol. 2012. PMID: 22922757 Free PMC article.
HIF2a inhibitors for the treatment of VHL disease.
Metelo AM, Noonan H, Iliopoulos O. Metelo AM, et al. Oncotarget. 2015 Sep 15;6(27):23036-7. doi: 10.18632/oncotarget.4564. Oncotarget. 2015. PMID: 26325097 Free PMC article. Review. No abstract available.
Metabolic requirements for cancer cell proliferation.
Keibler MA, Wasylenko TM, Kelleher JK, Iliopoulos O, Vander Heiden MG, Stephanopoulos G. Keibler MA, et al. Cancer Metab. 2016 Aug 18;4:16. doi: 10.1186/s40170-016-0156-6. eCollection 2016. Cancer Metab. 2016. PMID: 27540483 Free PMC article.
A roadmap for interpreting (13)C metabolite labeling patterns from cells.
Buescher JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H, Clish CB, DeBerardinis RJ, Feron O, Frezza C, Ghesquiere B, Gottlieb E, Hiller K, Jones RG, Kamphorst JJ, Kibbey RG, Kimmelman AC, Locasale JW, Lunt SY, Maddocks OD, Malloy C, Metallo CM, Meuillet EJ, Munger J, Nöh K, Rabinowitz JD, Ralser M, Sauer U, Stephanopoulos G, St-Pierre J, Tennant DA, Wittmann C, Vander Heiden MG, Vazquez A, Vousden K, Young JD, Zamboni N, Fendt SM. Buescher JM, et al. Curr Opin Biotechnol. 2015 Aug;34:189-201. doi: 10.1016/j.copbio.2015.02.003. Epub 2015 Feb 28. Curr Opin Biotechnol. 2015. PMID: 25731751 Free PMC article. Review.
43 results