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Page 1
BET bromodomain inhibition as a therapeutic strategy to target c-Myc.
Cell. 2011 Sep 16;146(6):904-17. doi: 10.1016/j.cell.2011.08.017. Epub 2011 Sep 1.
Cell. 2011.
PMID: 21889194
Free PMC article.
N-cadherin-mediated interaction with multiple myeloma cells inhibits osteoblast differentiation.
Groen RW, de Rooij MF, Kocemba KA, Reijmers RM, de Haan-Kramer A, Overdijk MB, Aalders L, Rozemuller H, Martens AC, Bergsagel PL, Kersten MJ, Pals ST, Spaargaren M.
Groen RW, et al.
Haematologica. 2011 Nov;96(11):1653-61. doi: 10.3324/haematol.2010.038133. Epub 2011 Aug 9.
Haematologica. 2011.
PMID: 21828122
Free PMC article.
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Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide.
Zhu YX, Braggio E, Shi CX, Bruins LA, Schmidt JE, Van Wier S, Chang XB, Bjorklund CC, Fonseca R, Bergsagel PL, Orlowski RZ, Stewart AK.
Zhu YX, et al.
Blood. 2011 Nov 3;118(18):4771-9. doi: 10.1182/blood-2011-05-356063. Epub 2011 Aug 22.
Blood. 2011.
PMID: 21860026
Free PMC article.
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CD28 expressed on malignant plasma cells induces a prosurvival and immunosuppressive microenvironment.
Nair JR, Carlson LM, Koorella C, Rozanski CH, Byrne GE, Bergsagel PL, Shaughnessy JP Jr, Boise LH, Chanan-Khan A, Lee KP.
Nair JR, et al.
J Immunol. 2011 Aug 1;187(3):1243-53. doi: 10.4049/jimmunol.1100016. Epub 2011 Jun 29.
J Immunol. 2011.
PMID: 21715687
Free PMC article.
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Lenalidomide, cyclophosphamide and dexamethasone (CRd) for newly diagnosed multiple myeloma: results from a phase 2 trial.
Kumar SK, Lacy MQ, Hayman SR, Stewart K, Buadi FK, Allred J, Laumann K, Greipp PR, Lust JA, Gertz MA, Zeldenrust SR, Bergsagel PL, Reeder CB, Witzig TE, Fonseca R, Russell SJ, Mikhael JR, Dingli D, Rajkumar SV, Dispenzieri A.
Kumar SK, et al.
Am J Hematol. 2011 Aug;86(8):640-5. doi: 10.1002/ajh.22053. Epub 2011 May 31.
Am J Hematol. 2011.
PMID: 21630308
Free PMC article.
Clinical Trial.
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Approach to the treatment of multiple myeloma: a clash of philosophies.
Rajkumar SV, Gahrton G, Bergsagel PL.
Rajkumar SV, et al.
Blood. 2011 Sep 22;118(12):3205-11. doi: 10.1182/blood-2011-06-297853. Epub 2011 Jul 25.
Blood. 2011.
PMID: 21791430
Free PMC article.
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International Myeloma Working Group consensus approach to the treatment of multiple myeloma patients who are candidates for autologous stem cell transplantation.
Cavo M, Rajkumar SV, Palumbo A, Moreau P, Orlowski R, Bladé J, Sezer O, Ludwig H, Dimopoulos MA, Attal M, Sonneveld P, Boccadoro M, Anderson KC, Richardson PG, Bensinger W, Johnsen HE, Kroeger N, Gahrton G, Bergsagel PL, Vesole DH, Einsele H, Jagannath S, Niesvizky R, Durie BG, San Miguel J, Lonial S; International Myeloma Working Group.
Cavo M, et al.
Blood. 2011 Jun 9;117(23):6063-73. doi: 10.1182/blood-2011-02-297325. Epub 2011 Mar 29.
Blood. 2011.
PMID: 21447828
Free PMC article.
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Pomalidomide plus low-dose dexamethasone in myeloma refractory to both bortezomib and lenalidomide: comparison of 2 dosing strategies in dual-refractory disease.
Lacy MQ, Allred JB, Gertz MA, Hayman SR, Short KD, Buadi F, Dispenzieri A, Kumar S, Greipp PR, Lust JA, Russell SJ, Dingli D, Zeldenrust S, Fonseca R, Bergsagel PL, Roy V, Stewart AK, Laumann K, Mandrekar SJ, Reeder C, Rajkumar SV, Mikhael JR.
Lacy MQ, et al.
Blood. 2011 Sep 15;118(11):2970-5. doi: 10.1182/blood-2011-04-348896. Epub 2011 Jun 20.
Blood. 2011.
PMID: 21690557
Free PMC article.
Clinical Trial.
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