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CRISPR-mediated direct mutation of cancer genes in the mouse liver.
Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T. Xue W, et al. Nature. 2014 Oct 16;514(7522):380-4. doi: 10.1038/nature13589. Epub 2014 Aug 6. Nature. 2014. PMID: 25119044 Free PMC article.
Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity.
Whitehead KA, Dorkin JR, Vegas AJ, Chang PH, Veiseh O, Matthews J, Fenton OS, Zhang Y, Olejnik KT, Yesilyurt V, Chen D, Barros S, Klebanov B, Novobrantseva T, Langer R, Anderson DG. Whitehead KA, et al. Nat Commun. 2014 Jun 27;5:4277. doi: 10.1038/ncomms5277. Nat Commun. 2014. PMID: 24969323 Free PMC article.
Small RNA combination therapy for lung cancer.
Xue W, Dahlman JE, Tammela T, Khan OF, Sood S, Dave A, Cai W, Chirino LM, Yang GR, Bronson R, Crowley DG, Sahay G, Schroeder A, Langer R, Anderson DG, Jacks T. Xue W, et al. Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):E3553-61. doi: 10.1073/pnas.1412686111. Epub 2014 Aug 11. Proc Natl Acad Sci U S A. 2014. PMID: 25114235 Free PMC article.
A versatile reporter system for CRISPR-mediated chromosomal rearrangements.
Li Y, Park AI, Mou H, Colpan C, Bizhanova A, Akama-Garren E, Joshi N, Hendrickson EA, Feldser D, Yin H, Anderson DG, Jacks T, Weng Z, Xue W. Li Y, et al. Genome Biol. 2015 May 28;16(1):111. doi: 10.1186/s13059-015-0680-7. Genome Biol. 2015. PMID: 26018130 Free PMC article.
Therapeutic siRNA silencing in inflammatory monocytes in mice.
Leuschner F, Dutta P, Gorbatov R, Novobrantseva TI, Donahoe JS, Courties G, Lee KM, Kim JI, Markmann JF, Marinelli B, Panizzi P, Lee WW, Iwamoto Y, Milstein S, Epstein-Barash H, Cantley W, Wong J, Cortez-Retamozo V, Newton A, Love K, Libby P, Pittet MJ, Swirski FK, Koteliansky V, Langer R, Weissleder R, Anderson DG, Nahrendorf M. Leuschner F, et al. Nat Biotechnol. 2011 Oct 9;29(11):1005-10. doi: 10.1038/nbt.1989. Nat Biotechnol. 2011. PMID: 21983520 Free PMC article.