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Prediction of postoperative recurrence-free survival in non-small cell lung cancer by using an internationally validated gene expression model.
Mitra R, Lee J, Jo J, Milani M, McClintick JN, Edenberg HJ, Kesler KA, Rieger KM, Badve S, Cummings OW, Mohiuddin A, Thomas DG, Luo X, Juliar BE, Li L, Mesaros C, Blair IA, Srirangam A, Kratzke RA, McDonald CJ, Kim J, Potter DA. Mitra R, et al. Clin Cancer Res. 2011 May 1;17(9):2934-46. doi: 10.1158/1078-0432.CCR-10-1803. Epub 2011 Jan 17. Clin Cancer Res. 2011. PMID: 21242119 Free PMC article.
CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET).
Mitra R, Guo Z, Milani M, Mesaros C, Rodriguez M, Nguyen J, Luo X, Clarke D, Lamba J, Schuetz E, Donner DB, Puli N, Falck JR, Capdevila J, Gupta K, Blair IA, Potter DA. Mitra R, et al. J Biol Chem. 2011 May 20;286(20):17543-59. doi: 10.1074/jbc.M110.198515. Epub 2011 Mar 14. J Biol Chem. 2011. PMID: 21402692 Free PMC article.