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Page 1
Iron in multiple myeloma.
VanderWall K, Daniels-Wells TR, Penichet M, Lichtenstein A. VanderWall K, et al. Crit Rev Oncog. 2013;18(5):449-61. doi: 10.1615/critrevoncog.2013007934. Crit Rev Oncog. 2013. PMID: 23879589 Free PMC article. Review.
The PP242 mammalian target of rapamycin (mTOR) inhibitor activates extracellular signal-regulated kinase (ERK) in multiple myeloma cells via a target of rapamycin complex 1 (TORC1)/eukaryotic translation initiation factor 4E (eIF-4E)/RAF pathway and activation is a mechanism of resistance.
Hoang B, Benavides A, Shi Y, Yang Y, Frost P, Gera J, Lichtenstein A. Hoang B, et al. J Biol Chem. 2012 Jun 22;287(26):21796-805. doi: 10.1074/jbc.M111.304626. Epub 2012 May 3. J Biol Chem. 2012. PMID: 22556409 Free PMC article.
Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor.
Hoang B, Frost P, Shi Y, Belanger E, Benavides A, Pezeshkpour G, Cappia S, Guglielmelli T, Gera J, Lichtenstein A. Hoang B, et al. Blood. 2010 Nov 25;116(22):4560-8. doi: 10.1182/blood-2010-05-285726. Epub 2010 Aug 4. Blood. 2010. PMID: 20686120 Free PMC article.
13 results