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Page 1
T antigen transgenic mouse models.
Sáenz Robles MT, Pipas JM. Sáenz Robles MT, et al. Semin Cancer Biol. 2009 Aug;19(4):229-35. doi: 10.1016/j.semcancer.2009.02.002. Epub 2009 Feb 14. Semin Cancer Biol. 2009. PMID: 19505650 Free PMC article. Review.
E2f8 mediates tumor suppression in postnatal liver development.
Kent LN, Rakijas JB, Pandit SK, Westendorp B, Chen HZ, Huntington JT, Tang X, Bae S, Srivastava A, Senapati S, Koivisto C, Martin CK, Cuitino MC, Perez M, Clouse JM, Chokshi V, Shinde N, Kladney R, Sun D, Perez-Castro A, Matondo RB, Nantasanti S, Mokry M, Huang K, Machiraju R, Fernandez S, Rosol TJ, Coppola V, Pohar KS, Pipas JM, Schmidt CR, de Bruin A, Leone G. Kent LN, et al. J Clin Invest. 2016 Aug 1;126(8):2955-69. doi: 10.1172/JCI85506. Epub 2016 Jul 25. J Clin Invest. 2016. PMID: 27454291 Free PMC article.
E2f3 in tumor macrophages promotes lung metastasis.
Trikha P, Sharma N, Pena C, Reyes A, Pécot T, Khurshid S, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Ostrowski MC, Leone G. Trikha P, et al. Oncogene. 2016 Jul 14;35(28):3636-46. doi: 10.1038/onc.2015.429. Epub 2015 Nov 9. Oncogene. 2016. PMID: 26549026 Free PMC article.
Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.
Liu H, Tang X, Srivastava A, Pécot T, Daniel P, Hemmelgarn B, Reyes S, Fackler N, Bajwa A, Kladney R, Koivisto C, Chen Z, Wang Q, Huang K, Machiraju R, Sáenz-Robles MT, Cantalupo P, Pipas JM, Leone G. Liu H, et al. Nat Cell Biol. 2015 Aug;17(8):1036-48. doi: 10.1038/ncb3210. Epub 2015 Jul 20. Nat Cell Biol. 2015. PMID: 26192440 Free PMC article.
Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.
Kent LN, Bae S, Tsai SY, Tang X, Srivastava A, Koivisto C, Martin CK, Ridolfi E, Miller GC, Zorko SM, Plevris E, Hadjiyannis Y, Perez M, Nolan E, Kladney R, Westendorp B, de Bruin A, Fernandez S, Rosol TJ, Pohar KS, Pipas JM, Leone G. Kent LN, et al. J Clin Invest. 2017 Mar 1;127(3):830-842. doi: 10.1172/JCI87583. Epub 2017 Jan 30. J Clin Invest. 2017. PMID: 28134624 Free PMC article.
18 results