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Page 1
Optical Control of Lysophosphatidic Acid Signaling.
Morstein J, Dacheux MA, Norman DD, Shemet A, Donthamsetti PC, Citir M, Frank JA, Schultz C, Isacoff EY, Parrill AL, Tigyi GJ, Trauner D. Morstein J, et al. J Am Chem Soc. 2020 Jun 17;142(24):10612-10616. doi: 10.1021/jacs.0c02154. Epub 2020 Jun 5. J Am Chem Soc. 2020. PMID: 32469525 Free PMC article.
Controlling cancer through the autotaxin-lysophosphatidic acid receptor axis.
Gotoh M, Fujiwara Y, Yue J, Liu J, Lee S, Fells J, Uchiyama A, Murakami-Murofushi K, Kennel S, Wall J, Patil R, Gupte R, Balazs L, Miller DD, Tigyi GJ. Gotoh M, et al. Biochem Soc Trans. 2012 Feb;40(1):31-6. doi: 10.1042/BST20110608. Biochem Soc Trans. 2012. PMID: 22260662 Free PMC article. Review.
Lipids: LPA activates TRPV1--and it hurts.
Tigyi G. Tigyi G. Nat Chem Biol. 2011 Dec 15;8(1):22-3. doi: 10.1038/nchembio.738. Nat Chem Biol. 2011. PMID: 22173354 Free PMC article.
FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells.
Tonelli F, Lim KG, Loveridge C, Long J, Pitson SM, Tigyi G, Bittman R, Pyne S, Pyne NJ. Tonelli F, et al. Cell Signal. 2010 Oct;22(10):1536-42. doi: 10.1016/j.cellsig.2010.05.022. Epub 2010 Jun 4. Cell Signal. 2010. PMID: 20570726 Free PMC article.
98 results