R01 CA085344/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2000	1
2001	1
2003	1
2005	2
2006	1
2007	3
2008	3
2009	1
2010	1
2011	2
2012	4
2013	4
2014	1
2015	2
2016	8
2017	4
2018	1
2019	5
2020	4
2021	3
2022	3
2023	3
2024	1
2025	0

1

Replication fork stability confers chemoresistance in BRCA-deficient cells.

Ray Chaudhuri A, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, de Ruiter JR, Daniel JA, Konstantinopoulos PA, Cortez D, Cantor SB, Fernandez-Capetillo O, Ge K, Jonkers J, Rottenberg S, Sharan SK, Nussenzweig A. Ray Chaudhuri A, et al. Nature. 2016 Jul 21;535(7612):382-7. doi: 10.1038/nature18325. Nature. 2016. PMID: 27443740 Free PMC article.

2

FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability.

Liu W, Polaczek P, Roubal I, Meng Y, Choe WC, Caron MC, Sedgeman CA, Xi Y, Liu C, Wu Q, Zheng L, Masson JY, Shen B, Campbell JL. Liu W, et al. Nucleic Acids Res. 2023 Sep 22;51(17):9144-9165. doi: 10.1093/nar/gkad624. Nucleic Acids Res. 2023. PMID: 37526271 Free PMC article.

3

Structure-specific nucleases: role in Okazaki fragment maturation.

Ma L, Sun H, Abeywardana T, Zheng L, Shen B. Ma L, et al. Trends Genet. 2022 Aug;38(8):793-796. doi: 10.1016/j.tig.2022.04.001. Epub 2022 Apr 28. Trends Genet. 2022. PMID: 35491358 Free PMC article.

4

RNA N⁶ -methyladenosine reader YTHDC1 is essential for TGF-beta-mediated metastasis of triple negative breast cancer.

Tan B, Zhou K, Liu W, Prince E, Qing Y, Li Y, Han L, Qin X, Su R, Pokharel SP, Yang L, Zhao Z, Shen C, Li W, Chen Z, Zhang Z, Deng X, Small A, Wang K, Leung K, Chen CW, Shen B, Chen J. Tan B, et al. Theranostics. 2022 Jul 18;12(13):5727-5743. doi: 10.7150/thno.71872. eCollection 2022. Theranostics. 2022. PMID: 35966596 Free PMC article.

5

O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth.

Rao X, Duan X, Mao W, Li X, Li Z, Li Q, Zheng Z, Xu H, Chen M, Wang PG, Wang Y, Shen B, Yi W. Rao X, et al. Nat Commun. 2015 Sep 24;6:8468. doi: 10.1038/ncomms9468. Nat Commun. 2015. PMID: 26399441 Free PMC article.

6

Error-prone, stress-induced 3' flap-based Okazaki fragment maturation supports cell survival.

Sun H, Lu Z, Singh A, Zhou Y, Zheng E, Zhou M, Wang J, Wu X, Hu Z, Gu Z, Campbell JL, Zheng L, Shen B. Sun H, et al. Science. 2021 Dec 3;374(6572):1252-1258. doi: 10.1126/science.abj1013. Epub 2021 Dec 2. Science. 2021. PMID: 34855483 Free PMC article.

7

A local ATR-dependent checkpoint pathway is activated by a site-specific replication fork block in human cells.

Ahmed-Seghir S, Jalan M, Grimsley HE, Sharma A, Twayana S, Kosiyatrakul ST, Thompson C, Schildkraut CL, Powell SN. Ahmed-Seghir S, et al. Elife. 2023 Aug 30;12:RP87357. doi: 10.7554/eLife.87357. Elife. 2023. PMID: 37647215 Free PMC article.

8

TRAF6 mediates human DNA2 polyubiquitination and nuclear localization to maintain nuclear genome integrity.

Meng Y, Liu C, Shen L, Zhou M, Liu W, Kowolik C, Campbell JL, Zheng L, Shen B. Meng Y, et al. Nucleic Acids Res. 2019 Aug 22;47(14):7564-7579. doi: 10.1093/nar/gkz537. Nucleic Acids Res. 2019. PMID: 31216032 Free PMC article.

9

Okazaki fragment maturation: DNA flap dynamics for cell proliferation and survival.

Sun H, Ma L, Tsai YF, Abeywardana T, Shen B, Zheng L. Sun H, et al. Trends Cell Biol. 2023 Mar;33(3):221-234. doi: 10.1016/j.tcb.2022.06.014. Epub 2022 Jul 22. Trends Cell Biol. 2023. PMID: 35879148 Free PMC article. Review.

10

Tryptophan derivatives regulate the transcription of Oct4 in stem-like cancer cells.

Cheng J, Li W, Kang B, Zhou Y, Song J, Dan S, Yang Y, Zhang X, Li J, Yin S, Cao H, Yao H, Zhu C, Yi W, Zhao Q, Xu X, Zheng M, Zheng S, Li L, Shen B, Wang YJ. Cheng J, et al. Nat Commun. 2015 Jun 10;6:7209. doi: 10.1038/ncomms8209. Nat Commun. 2015. PMID: 26059097 Free PMC article.

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