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Double click reaction for the acquisition of a highly potent and selective mPTPB inhibitor.
ChemMedChem. 2010 Dec 3;5(12):2051-6. doi: 10.1002/cmdc.201000348.
ChemMedChem. 2010.
PMID: 20957718
Free PMC article.
Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis.
Chen L, Zhou B, Zhang S, Wu L, Wang Y, Franzblau SG, Zhang ZY.
Chen L, et al.
ACS Med Chem Lett. 2010 Oct 14;1(7):355-359. doi: 10.1021/ml1001135.
ACS Med Chem Lett. 2010.
PMID: 21116447
Free PMC article.
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Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).
Zhang X, He Y, Liu S, Yu Z, Jiang ZX, Yang Z, Dong Y, Nabinger SC, Wu L, Gunawan AM, Wang L, Chan RJ, Zhang ZY.
Zhang X, et al.
J Med Chem. 2010 Mar 25;53(6):2482-93. doi: 10.1021/jm901645u.
J Med Chem. 2010.
PMID: 20170098
Free PMC article.
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