R01 CA044722-17/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

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Differentiation-inducing potency of the seco-steroid JK-1624F2-2 can be increased by combination with an antioxidant and a p38MAPK inhibitor which upregulates the JNK pathway.

Zhang J, Posner GH, Danilenko M, Studzinski GP. Zhang J, et al. J Steroid Biochem Mol Biol. 2007 Jun-Jul;105(1-5):140-9. doi: 10.1016/j.jsbmb.2007.01.003. Epub 2007 May 16. J Steroid Biochem Mol Biol. 2007. PMID: 17583492 Free PMC article.

Resistance to 1,25D-induced differentiation in human acute myeloid leukemia HL60-40AF cells is associated with reduced transcriptional activity and nuclear localization of the vitamin D receptor.

Garay E, Donnelly R, Wang X, Studzinski GP. Garay E, et al. J Cell Physiol. 2007 Dec;213(3):816-25. doi: 10.1002/jcp.21150. J Cell Physiol. 2007. PMID: 17520689 Free PMC article.

Calcitriol derivatives with two different side-chains at C-20. Part 4: further chain modifications that alter VDR-dependent monocytic differentiation potency in human leukemia cells.

Garay E, Jankowski P, Lizano P, Marczak S, Maehr H, Adorini L, Uskokovic MR, Studzinski GP. Garay E, et al. Bioorg Med Chem. 2007 Jul 1;15(13):4444-55. doi: 10.1016/j.bmc.2007.04.034. Epub 2007 Apr 25. Bioorg Med Chem. 2007. PMID: 17485214 Free PMC article.

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