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Inhibition of HIPK2 Alleviates Thoracic Aortic Disease in Mice With Progressively Severe Marfan Syndrome.
Caescu CI, Hansen J, Crockett B, Xiao W, Arnaud P, Spronck B, Weinberg A, Hashimoto T, Murtada SI, Borkar R, Gallo JM, Jondeau G, Boileau C, Humphrey JD, He JC, Iyengar R, Ramirez F. Caescu CI, et al. Arterioscler Thromb Vasc Biol. 2021 Sep;41(9):2483-2493. doi: 10.1161/ATVBAHA.121.316464. Epub 2021 Jul 29. Arterioscler Thromb Vasc Biol. 2021. PMID: 34320838 Free PMC article.
Systems pharmacology-based integration of human and mouse data for drug repurposing to treat thoracic aneurysms.
Hansen J, Galatioto J, Caescu CI, Arnaud P, Calizo RC, Spronck B, Murtada SI, Borkar R, Weinberg A, Azeloglu EU, Bintanel-Morcillo M, Gallo JM, Humphrey JD, Jondeau G, Boileau C, Ramirez F, Iyengar R. Hansen J, et al. JCI Insight. 2019 Jun 6;4(11):e127652. doi: 10.1172/jci.insight.127652. eCollection 2019 Jun 6. JCI Insight. 2019. PMID: 31167969 Free PMC article.