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Page 1
The multiple pathways to autoimmunity.
Theofilopoulos AN, Kono DH, Baccala R. Theofilopoulos AN, et al. Nat Immunol. 2017 Jun 20;18(7):716-724. doi: 10.1038/ni.3731. Nat Immunol. 2017. PMID: 28632714 Free PMC article. Review.
Sensors of the innate immune system: their link to rheumatic diseases.
Theofilopoulos AN, Gonzalez-Quintial R, Lawson BR, Koh YT, Stern ME, Kono DH, Beutler B, Baccala R. Theofilopoulos AN, et al. Nat Rev Rheumatol. 2010 Mar;6(3):146-56. doi: 10.1038/nrrheum.2009.278. Epub 2010 Feb 9. Nat Rev Rheumatol. 2010. PMID: 20142813 Free PMC article. Review.
TLRs and interferons: a central paradigm in autoimmunity.
Kono DH, Baccala R, Theofilopoulos AN. Kono DH, et al. Curr Opin Immunol. 2013 Dec;25(6):720-7. doi: 10.1016/j.coi.2013.10.006. Epub 2013 Nov 16. Curr Opin Immunol. 2013. PMID: 24246388 Free PMC article. Review.
Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant.
Wang RE, Wang Y, Zhang Y, Gabrelow C, Zhang Y, Chi V, Fu Q, Luo X, Wang D, Joseph S, Johnson K, Chatterjee AK, Wright TM, Nguyen-Tran VT, Teijaro J, Theofilopoulos AN, Schultz PG, Wang F. Wang RE, et al. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11501-11506. doi: 10.1073/pnas.1612803113. Epub 2016 Sep 23. Proc Natl Acad Sci U S A. 2016. PMID: 27663736 Free PMC article.
Type I interferon is a therapeutic target for virus-induced lethal vascular damage.
Baccala R, Welch MJ, Gonzalez-Quintial R, Walsh KB, Teijaro JR, Nguyen A, Ng CT, Sullivan BM, Zarpellon A, Ruggeri ZM, de la Torre JC, Theofilopoulos AN, Oldstone MB. Baccala R, et al. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8925-30. doi: 10.1073/pnas.1408148111. Epub 2014 Jun 2. Proc Natl Acad Sci U S A. 2014. PMID: 24889626 Free PMC article.
Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN.
Pollard KM, Escalante GM, Huang H, Haraldsson KM, Hultman P, Christy JM, Pawar RD, Mayeux JM, Gonzalez-Quintial R, Baccala R, Beutler B, Theofilopoulos AN, Kono DH. Pollard KM, et al. J Immunol. 2017 Dec 1;199(11):3739-3747. doi: 10.4049/jimmunol.1700332. Epub 2017 Oct 20. J Immunol. 2017. PMID: 29055005 Free PMC article.