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Interferon signaling in the nasal epithelium distinguishes among lethal and common cold respiratory viruses and is critical for viral clearance.
Otter CJ, Renner DM, Fausto A, Tan LH, Cohen NA, Weiss SR. Otter CJ, et al. bioRxiv [Preprint]. 2023 Dec 19:2023.12.18.571720. doi: 10.1101/2023.12.18.571720. bioRxiv. 2023. Update in: Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2402540121. doi: 10.1073/pnas.2402540121 PMID: 38187597 Free PMC article. Updated. Preprint.
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling.
Otter CJ, Bracci N, Parenti NA, Ye C, Asthana A, Blomqvist EK, Tan LH, Pfannenstiel JJ, Jackson N, Fehr AR, Silverman RH, Burke JM, Cohen NA, Martinez-Sobrido L, Weiss SR. Otter CJ, et al. Proc Natl Acad Sci U S A. 2024 Apr 9;121(15):e2320194121. doi: 10.1073/pnas.2320194121. Epub 2024 Apr 3. Proc Natl Acad Sci U S A. 2024. PMID: 38568967 Free PMC article.
Common Cold Coronavirus 229E Induces Higher Interferon Stimulating Gene Responses in Human Nasal Epithelial Cells from Patients with Chronic Rhinosinusitis with Polyposis.
Sell EA, Tan LH, Renner DM, Douglas J, Lee RJ, Kohanski MA, Bosso JV, Kennedy DW, Palmer JN, Adappa ND, Weiss SR, Cohen NA. Sell EA, et al. Am J Rhinol Allergy. 2025 Jan;39(1):13-20. doi: 10.1177/19458924241276274. Epub 2024 Nov 8. Am J Rhinol Allergy. 2025. PMID: 39513200 Free PMC article.
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling.
Otter CJ, Bracci N, Parenti NA, Ye C, Tan LH, Asthana A, Pfannenstiel JJ, Jackson N, Fehr AR, Silverman RH, Cohen NA, Martinez-Sobrido L, Weiss SR. Otter CJ, et al. bioRxiv [Preprint]. 2023 Nov 15:2023.11.15.566945. doi: 10.1101/2023.11.15.566945. bioRxiv. 2023. Update in: Proc Natl Acad Sci U S A. 2024 Apr 9;121(15):e2320194121. doi: 10.1073/pnas.2320194121 PMID: 38014074 Free PMC article. Updated. Preprint.
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