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Pathogenesis of Zika Virus Infection.
Giraldo MI, Gonzalez-Orozco M, Rajsbaum R. Giraldo MI, et al. Annu Rev Pathol. 2023 Jan 24;18:181-203. doi: 10.1146/annurev-pathmechdis-031521-034739. Epub 2022 Sep 23. Annu Rev Pathol. 2023. PMID: 36151059 Free PMC article. Review.
Dengue virus NS5 degrades ERC1 during infection to antagonize NF-kB activation.
Gonzalez Lopez Ledesma MM, Costa Navarro G, Pallares HM, Paletta A, De Maio F, Iglesias NG, Gebhard L, Oviedo Rouco S, Ojeda DS, de Borba L, Giraldo M, Rajsbaum R, Ceballos A, Krogan NJ, Shah PS, Gamarnik AV. Gonzalez Lopez Ledesma MM, et al. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2220005120. doi: 10.1073/pnas.2220005120. Epub 2023 May 30. Proc Natl Acad Sci U S A. 2023. PMID: 37252973 Free PMC article.
Lighting the way to host-directed immunotherapeutics.
van Tol S, Hage A, Rajsbaum R. van Tol S, et al. Cell Chem Biol. 2022 Jul 21;29(7):1067-1070. doi: 10.1016/j.chembiol.2022.06.009. Cell Chem Biol. 2022. PMID: 35868235 Free PMC article.
Ebola virus VP35 interacts non-covalently with ubiquitin chains to promote viral replication.
Rodríguez-Salazar CA, van Tol S, Mailhot O, Gonzalez-Orozco M, Galdino GT, Warren AN, Teruel N, Behera P, Afreen KS, Zhang L, Juelich TL, Smith JK, Zylber MI, Freiberg AN, Najmanovich RJ, Giraldo MI, Rajsbaum R. Rodríguez-Salazar CA, et al. PLoS Biol. 2024 Feb 29;22(2):e3002544. doi: 10.1371/journal.pbio.3002544. eCollection 2024 Feb. PLoS Biol. 2024. PMID: 38422166 Free PMC article.
TRIM7 ubiquitinates SARS-CoV-2 membrane protein to limit apoptosis and viral replication.
Gonzalez-Orozco M, Tseng HC, Hage A, Xia H, Behera P, Afreen K, Peñaflor-Tellez Y, Giraldo MI, Huante M, Puebla-Clark L, van Tol S, Odle A, Crown M, Teruel N, Shelite TR, Menachery V, Endsley M, Endsley JJ, Najmanovich RJ, Bashton M, Stephens R, Shi PY, Xie X, Freiberg AN, Rajsbaum R. Gonzalez-Orozco M, et al. bioRxiv [Preprint]. 2024 Jun 17:2024.06.17.599107. doi: 10.1101/2024.06.17.599107. bioRxiv. 2024. Update in: Nat Commun. 2024 Nov 30;15(1):10438. doi: 10.1038/s41467-024-54762-5 PMID: 38948778 Free PMC article. Updated. Preprint.
Ebola Virus VP35 Interacts Non-Covalently with Ubiquitin Chains to Promote Viral Replication Creating New Therapeutic Opportunities.
Rodríguez-Salazar CA, van Tol S, Mailhot O, Galdino G, Teruel N, Zhang L, Warren AN, González-Orozco M, Freiberg AN, Najmanovich RJ, Giraldo MI, Rajsbaum R. Rodríguez-Salazar CA, et al. bioRxiv [Preprint]. 2023 Jul 15:2023.07.14.549057. doi: 10.1101/2023.07.14.549057. bioRxiv. 2023. Update in: PLoS Biol. 2024 Feb 29;22(2):e3002544. doi: 10.1371/journal.pbio.3002544 PMID: 37503276 Free PMC article. Updated. Preprint.
Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly.
van Tol S, Kalveram B, Ilinykh PA, Ronk A, Huang K, Aguilera-Aguirre L, Bharaj P, Hage A, Atkins C, Giraldo MI, Wakamiya M, Gonzalez-Orozco M, Warren AN, Bukreyev A, Freiberg AN, Rajsbaum R. van Tol S, et al. PLoS Pathog. 2022 May 9;18(5):e1010532. doi: 10.1371/journal.ppat.1010532. eCollection 2022 May. PLoS Pathog. 2022. PMID: 35533195 Free PMC article.
12 results