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Saturation mutagenesis-reinforced functional assays for disease-related genes.
Ma K, Huang S, Ng KK, Lake NJ, Joseph S, Xu J, Lek A, Ge L, Woodman KG, Koczwara KE, Cohen J, Ho V, O'Connor CL, Brindley MA, Campbell KP, Lek M. Ma K, et al. Cell. 2024 Nov 14;187(23):6707-6724.e22. doi: 10.1016/j.cell.2024.08.047. Epub 2024 Sep 25. Cell. 2024. PMID: 39326416
Host and viral determinants for efficient SARS-CoV-2 infection of the human lung.
Chu H, Hu B, Huang X, Chai Y, Zhou D, Wang Y, Shuai H, Yang D, Hou Y, Zhang X, Yuen TT, Cai JP, Zhang AJ, Zhou J, Yuan S, To KK, Chan IH, Sit KY, Foo DC, Wong IY, Ng AT, Cheung TT, Law SY, Au WK, Brindley MA, Chen Z, Kok KH, Chan JF, Yuen KY. Chu H, et al. Nat Commun. 2021 Jan 8;12(1):134. doi: 10.1038/s41467-020-20457-w. Nat Commun. 2021. PMID: 33420022 Free PMC article.
Chikungunya Virus Release is Reduced by TIM-1 Receptors Through Binding of Envelope Phosphatidylserine.
Ballista JMR, Hoover AJ, Noble JT, Acciani MD, Miazgowicz KL, Harrison SA, Tabscott GAL, Duncan A, Barnes DN, Jimenez AR, Brindley MA. Ballista JMR, et al. bioRxiv [Preprint]. 2024 Jan 26:2024.01.25.577233. doi: 10.1101/2024.01.25.577233. bioRxiv. 2024. Update in: J Virol. 2024 Aug 20;98(8):e0077524. doi: 10.1128/jvi.00775-24 PMID: 38328121 Free PMC article. Updated. Preprint.
Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor.
Zhao P, Praissman JL, Grant OC, Cai Y, Xiao T, Rosenbalm KE, Aoki K, Kellman BP, Bridger R, Barouch DH, Brindley MA, Lewis NE, Tiemeyer M, Chen B, Woods RJ, Wells L. Zhao P, et al. Cell Host Microbe. 2020 Oct 7;28(4):586-601.e6. doi: 10.1016/j.chom.2020.08.004. Epub 2020 Aug 24. Cell Host Microbe. 2020. PMID: 32841605 Free PMC article.
15 results