R01 AI120670/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	1
2018	3
2019	4
2020	1
2021	2
2023	3
2024	1
2025	0

1

Characterization of spectinamide 1599 efficacy against different mycobacterial phenotypes.

Temrikar ZH, Kodidela S, Kumar S, Liu J, Robertson GT, Lee RE, Hickey AJ, Gonzalez-Juarrero M, Meibohm B. Temrikar ZH, et al. Tuberculosis (Edinb). 2023 May;140:102342. doi: 10.1016/j.tube.2023.102342. Epub 2023 Apr 20. Tuberculosis (Edinb). 2023. PMID: 37120915 Free PMC article.

2

Translational PK/PD of anti-infective therapeutics.

Rathi C, Lee RE, Meibohm B. Rathi C, et al. Drug Discov Today Technol. 2016 Sep-Dec;21-22:41-49. doi: 10.1016/j.ddtec.2016.08.004. Epub 2016 Oct 28. Drug Discov Today Technol. 2016. PMID: 27978987 Free PMC article. Review.

3

A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides.

Zohaib Ali M, Dutt TS, MacNeill A, Walz A, Pearce C, Lam H, Philp JS, Patterson J, Henao-Tamayo M, Lee R, Liu J, Robertson GT, Hickey AJ, Meibohm B, Gonzalez Juarrero M. Zohaib Ali M, et al. Elife. 2024 Oct 8;13:RP96190. doi: 10.7554/eLife.96190. Elife. 2024. PMID: 39378165 Free PMC article.

4

Development and Characterization of a Dry Powder Formulation for Anti-Tuberculosis Drug Spectinamide 1599.

Stewart IE, Lukka PB, Liu J, Meibohm B, Gonzalez-Juarrero M, Braunstein MS, Lee RE, Hickey AJ. Stewart IE, et al. Pharm Res. 2019 Jul 18;36(9):136. doi: 10.1007/s11095-019-2666-8. Pharm Res. 2019. PMID: 31321552 Free PMC article.

5

Comparative pharmacokinetics of spectinamide 1599 after subcutaneous and intrapulmonary aerosol administration in mice.

Rathi C, Lukka PB, Wagh S, Lee RE, Lenaerts AJ, Braunstein M, Hickey A, Gonzalez-Juarrero M, Meibohm B. Rathi C, et al. Tuberculosis (Edinb). 2019 Jan;114:119-122. doi: 10.1016/j.tube.2018.12.006. Epub 2018 Dec 31. Tuberculosis (Edinb). 2019. PMID: 30711150 Free PMC article.

6

Sterilization of Mycobacterium tuberculosis infected samples using methanol preserves anti-tuberculosis drugs for subsequent pharmacological testing studies.

Walz A, Lukka PB, Pearce C, Creissen E, Braunstein M, Hickey AJ, Meibohm B, Gonzalez-Juarrero M. Walz A, et al. Tuberculosis (Edinb). 2019 Jul;117:52-55. doi: 10.1016/j.tube.2019.06.002. Epub 2019 Jun 6. Tuberculosis (Edinb). 2019. PMID: 31378268 Free PMC article.

7

Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics.

Parmar KR, Lukka PB, Wagh S, Temrikar ZH, Liu J, Lee RE, Braunstein M, Hickey AJ, Robertson GT, Gonzalez-Juarrero M, Edginton A, Meibohm B. Parmar KR, et al. Pharmaceutics. 2023 Jun 17;15(6):1759. doi: 10.3390/pharmaceutics15061759. Pharmaceutics. 2023. PMID: 37376207 Free PMC article.

8

Preclinical Evaluation of Inhalational Spectinamide-1599 Therapy against Tuberculosis.

Gonzalez-Juarrero M, Lukka PB, Wagh S, Walz A, Arab J, Pearce C, Ali Z, Ryman JT, Parmar K, Temrikar Z, Munoz-Gutierrez J, Robertson GT, Liu J, Lenaerts AJ, Daley C, Lee RE, Braunstein M, Hickey AJ, Meibohm B. Gonzalez-Juarrero M, et al. ACS Infect Dis. 2021 Oct 8;7(10):2850-2863. doi: 10.1021/acsinfecdis.1c00213. Epub 2021 Sep 21. ACS Infect Dis. 2021. PMID: 34546724 Free PMC article.

9

Disposable Dosators Intended for Dry Powder Delivery to Mice.

Maloney SE, Stewart IE, Mecham JB, Gonzalez-Juarrero M, Meibohm B, Hickey AJ. Maloney SE, et al. J Vis Exp. 2023 Aug 18;(198). doi: 10.3791/65756. J Vis Exp. 2023. PMID: 37607097

10

Inhaled tigecycline is effective against Mycobacterium abscessus in vitro and in vivo.

Pearce C, Ruth MM, Pennings LJ, Wertheim HFL, Walz A, Hoefsloot W, Ruesen C, Muñoz Gutiérrez J, Gonzalez-Juarrero M, van Ingen J. Pearce C, et al. J Antimicrob Chemother. 2020 Jul 1;75(7):1889-1894. doi: 10.1093/jac/dkaa110. J Antimicrob Chemother. 2020. PMID: 32294173 Free PMC article.

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