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Page 1
Extended-spectrum antiprotozoal bumped kinase inhibitors: A review.
Van Voorhis WC, Doggett JS, Parsons M, Hulverson MA, Choi R, Arnold SLM, Riggs MW, Hemphill A, Howe DK, Mealey RH, Lau AOT, Merritt EA, Maly DJ, Fan E, Ojo KK. Van Voorhis WC, et al. Exp Parasitol. 2017 Sep;180:71-83. doi: 10.1016/j.exppara.2017.01.001. Epub 2017 Jan 5. Exp Parasitol. 2017. PMID: 28065755 Free PMC article. Review.
One health therapeutics: Target-Based drug development for cryptosporidiosis and other apicomplexa diseases.
Van Voorhis WC, Hulverson MA, Choi R, Huang W, Arnold SLM, Schaefer DA, Betzer DP, Vidadala RSR, Lee S, Whitman GR, Barrett LK, Maly DJ, Riggs MW, Fan E, Kennedy TJ, Tzipori S, Doggett JS, Winzer P, Anghel N, Imhof D, Müller J, Hemphill A, Ferre I, Sanchez-Sanchez R, Ortega-Mora LM, Ojo KK. Van Voorhis WC, et al. Vet Parasitol. 2021 Jan;289:109336. doi: 10.1016/j.vetpar.2020.109336. Epub 2020 Dec 15. Vet Parasitol. 2021. PMID: 33418437 Free PMC article. Review.
Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned.
Choi R, Hulverson MA, Huang W, Vidadala RSR, Whitman GR, Barrett LK, Schaefer DA, Betzer DP, Riggs MW, Doggett JS, Hemphill A, Ortega-Mora LM, McCloskey MC, Arnold SLM, Hackman RC, Marsh KC, Lynch JJ, Freiberg GM, Leroy BE, Kempf DJ, Choy RKM, de Hostos EL, Maly DJ, Fan E, Ojo KK, Van Voorhis WC. Choi R, et al. Int J Parasitol. 2020 May;50(5):413-422. doi: 10.1016/j.ijpara.2020.01.006. Epub 2020 Mar 26. Int J Parasitol. 2020. PMID: 32224121 Free PMC article. Review.
Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy.
Hulverson MA, Vinayak S, Choi R, Schaefer DA, Castellanos-Gonzalez A, Vidadala RSR, Brooks CF, Herbert GT, Betzer DP, Whitman GR, Sparks HN, Arnold SLM, Rivas KL, Barrett LK, White AC Jr, Maly DJ, Riggs MW, Striepen B, Van Voorhis WC, Ojo KK. Hulverson MA, et al. J Infect Dis. 2017 Apr 15;215(8):1275-1284. doi: 10.1093/infdis/jix120. J Infect Dis. 2017. PMID: 28329187 Free PMC article.
Endochin-like quinolones (ELQs) and bumped kinase inhibitors (BKIs): Synergistic and additive effects of combined treatments against Neospora caninum infection in vitro and in vivo.
Anghel N, Imhof D, Winzer P, Balmer V, Ramseier J, Haenggeli K, Choi R, Hulverson MA, Whitman GR, Arnold SLM, Ojo KK, Van Voorhis WC, Doggett JS, Ortega-Mora LM, Hemphill A. Anghel N, et al. Int J Parasitol Drugs Drug Resist. 2021 Dec;17:92-106. doi: 10.1016/j.ijpddr.2021.08.007. Epub 2021 Aug 28. Int J Parasitol Drugs Drug Resist. 2021. PMID: 34482255 Free PMC article.
Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis.
Hulverson MA, Choi R, Arnold SLM, Schaefer DA, Hemphill A, McCloskey MC, Betzer DP, Müller J, Vidadala RSR, Whitman GR, Rivas KL, Barrett LK, Hackman RC, Love MS, McNamara CW, Shaughnessy TK, Kondratiuk A, Kurnick M, Banfor PN, Lynch JJ, Freiberg GM, Kempf DJ, Maly DJ, Riggs MW, Ojo KK, Van Voorhis WC. Hulverson MA, et al. Int J Parasitol. 2017 Oct;47(12):753-763. doi: 10.1016/j.ijpara.2017.08.006. Epub 2017 Sep 9. Int J Parasitol. 2017. PMID: 28899690 Free PMC article.
In vitro efficacy of bumped kinase inhibitors against Besnoitia besnoiti tachyzoites.
Jiménez-Meléndez A, Ojo KK, Wallace AM, Smith TR, Hemphill A, Balmer V, Regidor-Cerrillo J, Ortega-Mora LM, Hehl AB, Fan E, Maly DJ, Van Voorhis WC, Álvarez-García G. Jiménez-Meléndez A, et al. Int J Parasitol. 2017 Oct;47(12):811-821. doi: 10.1016/j.ijpara.2017.08.005. Epub 2017 Sep 9. Int J Parasitol. 2017. PMID: 28899692
5-Aminopyrazole-4-Carboxamide-Based Compounds Prevent the Growth of Cryptosporidium parvum.
Huang W, Choi R, Hulverson MA, Zhang Z, McCloskey MC, Schaefer DA, Whitman GR, Barrett LK, Vidadala RSR, Riggs MW, Maly DJ, Van Voorhis WC, Ojo KK, Fan E. Huang W, et al. Antimicrob Agents Chemother. 2017 Jul 25;61(8):e00020-17. doi: 10.1128/AAC.00020-17. Print 2017 Aug. Antimicrob Agents Chemother. 2017. PMID: 28533246 Free PMC article.
57 results