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Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite Plasmodium falciparum.
J Med Chem. 2008 Jun 26;51(12):3649-53. doi: 10.1021/jm8001026. Epub 2008 Jun 4.
J Med Chem. 2008.
PMID: 18522386
Free PMC article.
Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice.
Gujjar R, Marwaha A, El Mazouni F, White J, White KL, Creason S, Shackleford DM, Baldwin J, Charman WN, Buckner FS, Charman S, Rathod PK, Phillips MA.
Gujjar R, et al.
J Med Chem. 2009 Apr 9;52(7):1864-72. doi: 10.1021/jm801343r.
J Med Chem. 2009.
PMID: 19296651
Free PMC article.
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