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Failures in clinical treatment of Staphylococcus aureus Infection with daptomycin are associated with alterations in surface charge, membrane phospholipid asymmetry, and drug binding.
Jones T, Yeaman MR, Sakoulas G, Yang SJ, Proctor RA, Sahl HG, Schrenzel J, Xiong YQ, Bayer AS. Jones T, et al. Antimicrob Agents Chemother. 2008 Jan;52(1):269-78. doi: 10.1128/AAC.00719-07. Epub 2007 Oct 22. Antimicrob Agents Chemother. 2008. PMID: 17954690 Free PMC article.
Reporter metabolite analysis of transcriptional profiles of a Staphylococcus aureus strain with normal phenotype and its isogenic hemB mutant displaying the small-colony-variant phenotype.
Seggewiss J, Becker K, Kotte O, Eisenacher M, Yazdi MR, Fischer A, McNamara P, Al Laham N, Proctor R, Peters G, Heinemann M, von Eiff C. Seggewiss J, et al. J Bacteriol. 2006 Nov;188(22):7765-77. doi: 10.1128/JB.00774-06. Epub 2006 Sep 15. J Bacteriol. 2006. PMID: 16980462 Free PMC article.
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