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Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation.
Finet O, Yague-Sanz C, Krüger LK, Tran P, Migeot V, Louski M, Nevers A, Rougemaille M, Sun J, Ernst FGM, Wacheul L, Wery M, Morillon A, Dedon P, Lafontaine DLJ, Hermand D. Finet O, et al. Mol Cell. 2022 Jan 20;82(2):404-419.e9. doi: 10.1016/j.molcel.2021.11.003. Epub 2021 Nov 18. Mol Cell. 2022. PMID: 34798057 Free PMC article.
Discovery adductomics provides a comprehensive portrait of tissue-, age- and sex-specific DNA modifications in rodents and humans.
Guilbaud A, Ghanegolmohammadi F, Wang Y, Leng J, Kreymerman A, Gamboa Varela J, Garbern J, Elwell H, Cao F, Ricci-Blair EM, Liang C, Balamkundu S, Vidoudez C, DeMott MS, Bedi K, Margulies KB, Bennett DA, Palmer AA, Barkley-Levenson A, Lee RT, Dedon PC. Guilbaud A, et al. Nucleic Acids Res. 2023 Nov 10;51(20):10829-10845. doi: 10.1093/nar/gkad822. Nucleic Acids Res. 2023. PMID: 37843128 Free PMC article.