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In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer's disease pathology and cognitive decline.
Jacobs HIL, Becker JA, Kwong K, Engels-Domínguez N, Prokopiou PC, Papp KV, Properzi M, Hampton OL, d'Oleire Uquillas F, Sanchez JS, Rentz DM, El Fakhri G, Normandin MD, Price JC, Bennett DA, Sperling RA, Johnson KA. Jacobs HIL, et al. Sci Transl Med. 2021 Sep 22;13(612):eabj2511. doi: 10.1126/scitranslmed.abj2511. Epub 2021 Sep 22. Sci Transl Med. 2021. PMID: 34550726 Free PMC article.
Locus coeruleus activity while awake is associated with REM sleep quality in older individuals.
Koshmanova E, Berger A, Beckers E, Campbell I, Mortazavi N, Sharifpour R, Paparella I, Balda F, Berthomier C, Degueldre C, Salmon E, Lamalle L, Bastin C, Van Egroo M, Phillips C, Maquet P, Collette F, Muto V, Chylinski D, Jacobs HI, Talwar P, Sherif S, Vandewalle G. Koshmanova E, et al. JCI Insight. 2023 Oct 23;8(20):e172008. doi: 10.1172/jci.insight.172008. JCI Insight. 2023. PMID: 37698926 Free PMC article.
28 results