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Page 1
Emerging strategies to boost thymic function.
Holländer GA, Krenger W, Blazar BR. Holländer GA, et al. Curr Opin Pharmacol. 2010 Aug;10(4):443-53. doi: 10.1016/j.coph.2010.04.008. Epub 2010 May 4. Curr Opin Pharmacol. 2010. PMID: 20447867 Free PMC article. Review.
Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy.
Bouchlaka MN, Sckisel GD, Chen M, Mirsoian A, Zamora AE, Maverakis E, Wilkins DE, Alderson KL, Hsiao HH, Weiss JM, Monjazeb AM, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Redelman D, Taub DD, Murphy WJ. Bouchlaka MN, et al. J Exp Med. 2013 Oct 21;210(11):2223-37. doi: 10.1084/jem.20131219. Epub 2013 Sep 30. J Exp Med. 2013. PMID: 24081947 Free PMC article.
CD43 regulates the threshold for T cell activation by targeting Cbl functions.
Pedraza-Alva G, Mérida LB, del Rio R, Fierro NA, Cruz-Muñoz ME, Olivares N, Melchy E, Igras V, Holländer GA, Burakoff SJ, Rosenstein Y. Pedraza-Alva G, et al. IUBMB Life. 2011 Oct;63(10):940-8. doi: 10.1002/iub.554. Epub 2011 Sep 9. IUBMB Life. 2011. PMID: 21905200 Free PMC article.
Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice.
Mirsoian A, Bouchlaka MN, Sckisel GD, Chen M, Pai CC, Maverakis E, Spencer RG, Fishbein KW, Siddiqui S, Monjazeb AM, Martin B, Maudsley S, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Taub DD, Murphy WJ. Mirsoian A, et al. J Exp Med. 2014 Nov 17;211(12):2373-83. doi: 10.1084/jem.20140116. Epub 2014 Nov 3. J Exp Med. 2014. PMID: 25366964 Free PMC article.
MicroRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection.
Zuklys S, Mayer CE, Zhanybekova S, Stefanski HE, Nusspaumer G, Gill J, Barthlott T, Chappaz S, Nitta T, Dooley J, Nogales-Cadenas R, Takahama Y, Finke D, Liston A, Blazar BR, Pascual-Montano A, Holländer GA. Zuklys S, et al. J Immunol. 2012 Oct 15;189(8):3894-904. doi: 10.4049/jimmunol.1200783. Epub 2012 Sep 12. J Immunol. 2012. PMID: 22972926 Free PMC article.
Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation.
Kelly RM, Goren EM, Taylor PA, Mueller SN, Stefanski HE, Osborn MJ, Scott HS, Komarova EA, Gudkov AV, Holländer GA, Blazar BR. Kelly RM, et al. Blood. 2010 Feb 4;115(5):1088-97. doi: 10.1182/blood-2009-05-223198. Epub 2009 Dec 4. Blood. 2010. PMID: 19965631 Free PMC article.