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Page 1
Piezo1 channel activation mimics high glucose as a stimulator of insulin release.
Deivasikamani V, Dhayalan S, Abudushalamu Y, Mughal R, Visnagri A, Cuthbertson K, Scragg JL, Munsey TS, Viswambharan H, Muraki K, Foster R, Sivaprasadarao A, Kearney MT, Beech DJ, Sukumar P. Deivasikamani V, et al. Sci Rep. 2019 Nov 14;9(1):16876. doi: 10.1038/s41598-019-51518-w. Sci Rep. 2019. PMID: 31727906 Free PMC article.
Endothelial IGF-1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity.
Haywood NJ, Luk C, Bridge KI, Drozd M, Makava N, Skromna A, Maccannell A, Ozber CH, Warmke N, Wilkinson CG, Watt NT, Koch-Paszkowski J, Teh I, Boyle JH, Smart S, Schneider JE, Yuldasheva NY, Roberts LD, Beech DJ, Sukumar P, Wheatcroft SB, Cubbon RM, Kearney MT. Haywood NJ, et al. EMBO Rep. 2021 May 5;22(5):e50767. doi: 10.15252/embr.202050767. Epub 2021 May 2. EMBO Rep. 2021. PMID: 33934497 Free PMC article.
Attenuation of oxidative stress-induced lesions in skeletal muscle in a mouse model of obesity-independent hyperlipidaemia and atherosclerosis through the inhibition of Nox2 activity.
Sfyri PP, Yuldasheva NY, Tzimou A, Giallourou N, Crispi V, Aburima A, Beltran-Alvarez P, Patel K, Mougios V, Swann JR, Kearney MT, Matsakas A. Sfyri PP, et al. Free Radic Biol Med. 2018 Dec;129:504-519. doi: 10.1016/j.freeradbiomed.2018.10.422. Epub 2018 Oct 17. Free Radic Biol Med. 2018. PMID: 30342191 Free article.
Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance-related vascular damage.
Maqbool A, Watt NT, Haywood N, Viswambharan H, Skromna A, Makava N, Visnagri A, Shawer HM, Bridge K, Muminov SK, Griffin K, Beech DJ, Wheatcroft SB, Porter KE, Simmons KJ, Sukumar P, Shah AM, Cubbon RM, Kearney MT, Yuldasheva NY. Maqbool A, et al. Am J Physiol Cell Physiol. 2020 Jul 1;319(1):C64-C74. doi: 10.1152/ajpcell.00389.2019. Epub 2020 May 13. Am J Physiol Cell Physiol. 2020. PMID: 32401607 Free PMC article.