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Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1.
Shin HR, Citron YR, Wang L, Tribouillard L, Goul CS, Stipp R, Sugasawa Y, Jain A, Samson N, Lim CY, Davis OB, Castaneda-Carpio D, Qian M, Nomura DK, Perera RM, Park E, Covey DF, Laplante M, Evers AS, Zoncu R. Shin HR, et al. Science. 2022 Sep 16;377(6612):1290-1298. doi: 10.1126/science.abg6621. Epub 2022 Aug 25. Science. 2022. PMID: 36007018 Free PMC article.
Neurosteroid influence on affective tone.
Walton NL, Antonoudiou P, Maguire JL. Walton NL, et al. Neurosci Biobehav Rev. 2023 Sep;152:105327. doi: 10.1016/j.neubiorev.2023.105327. Epub 2023 Jul 25. Neurosci Biobehav Rev. 2023. PMID: 37499891 Free PMC article. Review.
Neurosteroid enantiomers as potentially novel neurotherapeutics.
Covey DF, Evers AS, Izumi Y, Maguire JL, Mennerick SJ, Zorumski CF. Covey DF, et al. Neurosci Biobehav Rev. 2023 Jun;149:105191. doi: 10.1016/j.neubiorev.2023.105191. Epub 2023 Apr 20. Neurosci Biobehav Rev. 2023. PMID: 37085023 Free PMC article. Review.
Glaucoma and microglia-induced neuroinflammation.
Ishikawa M, Izumi Y, Sato K, Sato T, Zorumski CF, Kunikata H, Nakazawa T. Ishikawa M, et al. Front Ophthalmol (Lausanne). 2023 Feb 27;3:1132011. doi: 10.3389/fopht.2023.1132011. eCollection 2023. Front Ophthalmol (Lausanne). 2023. PMID: 38983051 Free PMC article. Review.
5β-Dihydrosteroids: Formation and Properties.
Penning TM, Covey DF. Penning TM, et al. Int J Mol Sci. 2024 Aug 14;25(16):8857. doi: 10.3390/ijms25168857. Int J Mol Sci. 2024. PMID: 39201544 Free PMC article. Review.
Endogenous recapitulation of Alzheimer's disease neuropathology through human 3D direct neuronal reprogramming.
Sun Z, Kwon JS, Ren Y, Chen S, Cates K, Lu X, Walker CK, Karahan H, Sviben S, Fitzpatrick JAJ, Valdez C, Houlden H, Karch CM, Bateman RJ, Sato C, Mennerick SJ, Diamond MI, Kim J, Tanzi RE, Holtzman DM, Yoo AS. Sun Z, et al. bioRxiv [Preprint]. 2023 May 25:2023.05.24.542155. doi: 10.1101/2023.05.24.542155. bioRxiv. 2023. Update in: Science. 2024 Aug 2;385(6708):adl2992. doi: 10.1126/science.adl2992 PMID: 37292658 Free PMC article. Updated. Preprint.
52 results