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Year Number of Results
2013 8
2014 125
2015 26
2016 50
2017 23
2018 17
2019 38
2020 42
2021 17
2022 13
2023 6
2024 7

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343 results

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Page 1
Multivalent Small-Molecule Pan-RAS Inhibitors.
Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, Yang WS, Tong L, Olive KP, Ferrando A, Stockwell BR. Welsch ME, et al. Cell. 2017 Feb 23;168(5):878-889.e29. doi: 10.1016/j.cell.2017.02.006. Cell. 2017. PMID: 28235199 Free PMC article.
Targeting a neoantigen derived from a common TP53 mutation.
Hsiue EH, Wright KM, Douglass J, Hwang MS, Mog BJ, Pearlman AH, Paul S, DiNapoli SR, Konig MF, Wang Q, Schaefer A, Miller MS, Skora AD, Azurmendi PA, Murphy MB, Liu Q, Watson E, Li Y, Pardoll DM, Bettegowda C, Papadopoulos N, Kinzler KW, Vogelstein B, Gabelli SB, Zhou S. Hsiue EH, et al. Science. 2021 Mar 5;371(6533):eabc8697. doi: 10.1126/science.abc8697. Epub 2021 Mar 1. Science. 2021. PMID: 33649166 Free PMC article.
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS. Huang YH, et al. Nature. 2015 Jan 15;517(7534):386-90. doi: 10.1038/nature13848. Epub 2014 Oct 26. Nature. 2015. PMID: 25363763 Free PMC article.
T-UCRs with digestive and respiratory diseases.
Wang Y, Zhou D, Feng Y, Chen G, Li N. Wang Y, et al. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127306. doi: 10.1016/j.bmcl.2020.127306. Epub 2020 Jun 2. Bioorg Med Chem Lett. 2020. PMID: 32631526 Review.
Approximating lattice similarity.
Andrews LC, Bernstein HJ, Sauter NK. Andrews LC, et al. Acta Crystallogr A Found Adv. 2023 Sep 1;79(Pt 5):480-484. doi: 10.1107/S2053273323003200. Epub 2023 Jul 24. Acta Crystallogr A Found Adv. 2023. PMID: 37485824 Free PMC article.
Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen.
Wright KM, DiNapoli SR, Miller MS, Aitana Azurmendi P, Zhao X, Yu Z, Chakrabarti M, Shi W, Douglass J, Hwang MS, Hsiue EH, Mog BJ, Pearlman AH, Paul S, Konig MF, Pardoll DM, Bettegowda C, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S, Gabelli SB. Wright KM, et al. Nat Commun. 2023 Aug 21;14(1):5063. doi: 10.1038/s41467-023-40821-w. Nat Commun. 2023. PMID: 37604828 Free PMC article.
Designed and biologically active protein lattices.
Wang ST, Minevich B, Liu J, Zhang H, Nykypanchuk D, Byrnes J, Liu W, Bershadsky L, Liu Q, Wang T, Ren G, Gang O. Wang ST, et al. Nat Commun. 2021 Jun 17;12(1):3702. doi: 10.1038/s41467-021-23966-4. Nat Commun. 2021. PMID: 34140491 Free PMC article.
343 results