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Page 1
tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors.
Berghmans S, Murphey RD, Wienholds E, Neuberg D, Kutok JL, Fletcher CD, Morris JP, Liu TX, Schulte-Merker S, Kanki JP, Plasterk R, Zon LI, Look AT. Berghmans S, et al. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):407-12. doi: 10.1073/pnas.0406252102. Epub 2005 Jan 3. Proc Natl Acad Sci U S A. 2005. PMID: 15630097 Free PMC article.
Human HTm4 is a hematopoietic cell cycle regulator.
Donato JL, Ko J, Kutok JL, Cheng T, Shirakawa T, Mao XQ, Beach D, Scadden DT, Sayegh MH, Adra CN. Donato JL, et al. J Clin Invest. 2002 Jan;109(1):51-8. doi: 10.1172/JCI14025. J Clin Invest. 2002. PMID: 11781350 Free PMC article.
Proteasome inhibition causes regression of leukemia and abrogates BCR-ABL-induced evasion of apoptosis in part through regulation of forkhead tumor suppressors.
Jagani Z, Song K, Kutok JL, Dewar MR, Melet A, Santos T, Grassian A, Ghaffari S, Wu C, Yeckes-Rodin H, Ren R, Miller K, Khosravi-Far R. Jagani Z, et al. Cancer Res. 2009 Aug 15;69(16):6546-55. doi: 10.1158/0008-5472.CAN-09-0605. Epub 2009 Aug 4. Cancer Res. 2009. PMID: 19654305 Free PMC article.