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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2017 1
2018 3
2019 23
2020 30
2021 39
2022 46
2023 44
2024 67
2025 2

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244 results

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Page 1
Targeting a neoantigen derived from a common TP53 mutation.
Hsiue EH, Wright KM, Douglass J, Hwang MS, Mog BJ, Pearlman AH, Paul S, DiNapoli SR, Konig MF, Wang Q, Schaefer A, Miller MS, Skora AD, Azurmendi PA, Murphy MB, Liu Q, Watson E, Li Y, Pardoll DM, Bettegowda C, Papadopoulos N, Kinzler KW, Vogelstein B, Gabelli SB, Zhou S. Hsiue EH, et al. Science. 2021 Mar 5;371(6533):eabc8697. doi: 10.1126/science.abc8697. Epub 2021 Mar 1. Science. 2021. PMID: 33649166 Free PMC article.
De novo designed proteins neutralize lethal snake venom toxins.
Torres SV, Valle MB, Mackessy SP, Menzies SK, Casewell NR, Ahmadi S, Burlet NJ, Muratspahić E, Sappington I, Overath MD, Rivera-de-Torre E, Ledergerber J, Laustsen AH, Boddum K, Bera AK, Kang A, Brackenbrough E, Cardoso IA, Crittenden EP, Edge RJ, Decarreau J, Ragotte RJ, Pillai AS, Abedi M, Han HL, Gerben SR, Murray A, Skotheim R, Stuart L, Stewart L, Fryer TJA, Jenkins TP, Baker D. Torres SV, et al. Res Sq [Preprint]. 2024 May 17:rs.3.rs-4402792. doi: 10.21203/rs.3.rs-4402792/v1. Res Sq. 2024. PMID: 38798548 Free PMC article. Preprint.
Binding and sensing diverse small molecules using shape-complementary pseudocycles.
An L, Said M, Tran L, Majumder S, Goreshnik I, Lee GR, Juergens D, Dauparas J, Anishchenko I, Coventry B, Bera AK, Kang A, Levine PM, Alvarez V, Pillai A, Norn C, Feldman D, Zorine D, Hicks DR, Li X, Sanchez MG, Vafeados DK, Salveson PJ, Vorobieva AA, Baker D. An L, et al. Science. 2024 Jul 19;385(6706):276-282. doi: 10.1126/science.adn3780. Epub 2024 Jul 18. Science. 2024. PMID: 39024436 Free PMC article.
A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models.
Yu X, Li D, Kottur J, Shen Y, Kim HS, Park KS, Tsai YH, Gong W, Wang J, Suzuki K, Parker J, Herring L, Kaniskan HÜ, Cai L, Jain R, Liu J, Aggarwal AK, Wang GG, Jin J. Yu X, et al. Sci Transl Med. 2021 Sep 29;13(613):eabj1578. doi: 10.1126/scitranslmed.abj1578. Epub 2021 Sep 29. Sci Transl Med. 2021. PMID: 34586829 Free PMC article.
Inhibitors of bacterial H2S biogenesis targeting antibiotic resistance and tolerance.
Shatalin K, Nuthanakanti A, Kaushik A, Shishov D, Peselis A, Shamovsky I, Pani B, Lechpammer M, Vasilyev N, Shatalina E, Rebatchouk D, Mironov A, Fedichev P, Serganov A, Nudler E. Shatalin K, et al. Science. 2021 Jun 11;372(6547):1169-1175. doi: 10.1126/science.abd8377. Science. 2021. PMID: 34112687 Free PMC article.
Diffusing protein binders to intrinsically disordered proteins.
Liu C, Wu K, Choi H, Han H, Zhang X, Watson JL, Shijo S, Bera AK, Kang A, Brackenbrough E, Coventry B, Hick DR, Hoofnagle AN, Zhu P, Li X, Decarreau J, Gerben SR, Yang W, Wang X, Lamp M, Murray A, Bauer M, Baker D. Liu C, et al. bioRxiv [Preprint]. 2024 Jul 16:2024.07.16.603789. doi: 10.1101/2024.07.16.603789. bioRxiv. 2024. PMID: 39071267 Free PMC article. Preprint.
Metal-Binding Q-Proline Macrocycles.
Northrup JD, Wiener JA, Hurley MFD, Hou CD, Keller TM, Baxter RHG, Zdilla MJ, Voelz VA, Schafmeister CE. Northrup JD, et al. J Org Chem. 2021 Mar 19;86(6):4867-4876. doi: 10.1021/acs.joc.1c00116. Epub 2021 Feb 26. J Org Chem. 2021. PMID: 33635647
Approximating lattice similarity.
Andrews LC, Bernstein HJ, Sauter NK. Andrews LC, et al. Acta Crystallogr A Found Adv. 2023 Sep 1;79(Pt 5):480-484. doi: 10.1107/S2053273323003200. Epub 2023 Jul 24. Acta Crystallogr A Found Adv. 2023. PMID: 37485824 Free PMC article.
Structural insights into melatonin receptors.
Stauch B, Johansson LC, Cherezov V. Stauch B, et al. FEBS J. 2020 Apr;287(8):1496-1510. doi: 10.1111/febs.15128. Epub 2019 Nov 23. FEBS J. 2020. PMID: 31693784 Free PMC article. Review.
Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.
Sinatra L, Vogelmann A, Friedrich F, Tararina MA, Neuwirt E, Colcerasa A, König P, Toy L, Yesiloglu TZ, Hilscher S, Gaitzsch L, Papenkordt N, Zhai S, Zhang L, Romier C, Einsle O, Sippl W, Schutkowski M, Gross O, Bendas G, Christianson DW, Hansen FK, Jung M, Schiedel M. Sinatra L, et al. J Med Chem. 2023 Nov 9;66(21):14787-14814. doi: 10.1021/acs.jmedchem.3c01385. Epub 2023 Oct 30. J Med Chem. 2023. PMID: 37902787 Free PMC article.
244 results