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Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.
Tirosh I, Izar B, Prakadan SM, Wadsworth MH 2nd, Treacy D, Trombetta JJ, Rotem A, Rodman C, Lian C, Murphy G, Fallahi-Sichani M, Dutton-Regester K, Lin JR, Cohen O, Shah P, Lu D, Genshaft AS, Hughes TK, Ziegler CG, Kazer SW, Gaillard A, Kolb KE, Villani AC, Johannessen CM, Andreev AY, Van Allen EM, Bertagnolli M, Sorger PK, Sullivan RJ, Flaherty KT, Frederick DT, Jané-Valbuena J, Yoon CH, Rozenblatt-Rosen O, Shalek AK, Regev A, Garraway LA. Tirosh I, et al. Science. 2016 Apr 8;352(6282):189-96. doi: 10.1126/science.aad0501. Science. 2016. PMID: 27124452 Free PMC article.
BAP1 has a survival role in cutaneous melanoma.
Kumar R, Taylor M, Miao B, Ji Z, Njauw JC, Jönsson G, Frederick DT, Tsao H. Kumar R, et al. J Invest Dermatol. 2015 Apr;135(4):1089-1097. doi: 10.1038/jid.2014.528. Epub 2014 Dec 18. J Invest Dermatol. 2015. PMID: 25521456 Free PMC article.
MITF Modulates Therapeutic Resistance through EGFR Signaling.
Ji Z, Erin Chen Y, Kumar R, Taylor M, Jenny Njauw CN, Miao B, Frederick DT, Wargo JA, Flaherty KT, Jönsson G, Tsao H. Ji Z, et al. J Invest Dermatol. 2015 Jul;135(7):1863-1872. doi: 10.1038/jid.2015.105. Epub 2015 Mar 19. J Invest Dermatol. 2015. PMID: 25789707 Free PMC article.
Skin β-endorphin mediates addiction to UV light.
Fell GL, Robinson KC, Mao J, Woolf CJ, Fisher DE. Fell GL, et al. Cell. 2014 Jun 19;157(7):1527-34. doi: 10.1016/j.cell.2014.04.032. Cell. 2014. PMID: 24949966 Free PMC article.
Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment.
Friedman AA, Amzallag A, Pruteanu-Malinici I, Baniya S, Cooper ZA, Piris A, Hargreaves L, Igras V, Frederick DT, Lawrence DP, Haber DA, Flaherty KT, Wargo JA, Ramaswamy S, Benes CH, Fisher DE. Friedman AA, et al. PLoS One. 2015 Oct 13;10(10):e0140310. doi: 10.1371/journal.pone.0140310. eCollection 2015. PLoS One. 2015. PMID: 26461489 Free PMC article.