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Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins.
J Am Chem Soc. 2011 Oct 26;133(42):16958-69. doi: 10.1021/ja206279b. Epub 2011 Sep 29.
J Am Chem Soc. 2011.
PMID: 21916458
Free PMC article.
The structure of Abeta42 C-terminal fragments probed by a combined experimental and theoretical study.
Wu C, Murray MM, Bernstein SL, Condron MM, Bitan G, Shea JE, Bowers MT.
Wu C, et al.
J Mol Biol. 2009 Mar 27;387(2):492-501. doi: 10.1016/j.jmb.2009.01.029. Epub 2009 Jan 23.
J Mol Biol. 2009.
PMID: 19356595
Free PMC article.
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The binding of thioflavin T and its neutral analog BTA-1 to protofibrils of the Alzheimer's disease Abeta(16-22) peptide probed by molecular dynamics simulations.
Wu C, Wang Z, Lei H, Duan Y, Bowers MT, Shea JE.
Wu C, et al.
J Mol Biol. 2008 Dec 19;384(3):718-29. doi: 10.1016/j.jmb.2008.09.062. Epub 2008 Oct 7.
J Mol Biol. 2008.
PMID: 18851978
Free PMC article.
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