NS28471/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1991	2
1992	3
1993	1
1995	1
1996	2
1997	3
1998	1
2000	1
2001	2
2002	4
2003	2
2004	1
2006	1
2007	2
2009	4
2010	1
2011	2
2012	1
2016	1
2025	0

1

The structure and function of G-protein-coupled receptors.

Rosenbaum DM, Rasmussen SG, Kobilka BK. Rosenbaum DM, et al. Nature. 2009 May 21;459(7245):356-63. doi: 10.1038/nature08144. Nature. 2009. PMID: 19458711 Free PMC article. Review.

2

G protein-coupled receptors. II. Mechanism of agonist activation.

Gether U, Kobilka BK. Gether U, et al. J Biol Chem. 1998 Jul 17;273(29):17979-82. doi: 10.1074/jbc.273.29.17979. J Biol Chem. 1998. PMID: 9660746 Free article. Review. No abstract available.

3

Structure-based discovery of beta2-adrenergic receptor ligands.

Kolb P, Rosenbaum DM, Irwin JJ, Fung JJ, Kobilka BK, Shoichet BK. Kolb P, et al. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6843-8. doi: 10.1073/pnas.0812657106. Epub 2009 Apr 2. Proc Natl Acad Sci U S A. 2009. PMID: 19342484 Free PMC article.

4

Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor.

Gether U, Lin S, Ghanouni P, Ballesteros JA, Weinstein H, Kobilka BK. Gether U, et al. EMBO J. 1997 Nov 17;16(22):6737-47. doi: 10.1093/emboj/16.22.6737. EMBO J. 1997. PMID: 9362488 Free PMC article.

5

Allosteric modulation of beta2-adrenergic receptor by Zn(2+).

Swaminath G, Steenhuis J, Kobilka B, Lee TW. Swaminath G, et al. Mol Pharmacol. 2002 Jan;61(1):65-72. doi: 10.1124/mol.61.1.65. Mol Pharmacol. 2002. PMID: 11752207

6

Identification of intramolecular interactions in adrenergic receptors.

Suryanarayana S, von Zastrow M, Kobilka BK. Suryanarayana S, et al. J Biol Chem. 1992 Nov 5;267(31):21991-4. J Biol Chem. 1992. PMID: 1331041 Free article.

7

Functional immobilization of a ligand-activated G-protein-coupled receptor.

Neumann L, Wohland T, Whelan RJ, Zare RN, Kobilka BK. Neumann L, et al. Chembiochem. 2002 Oct 4;3(10):993-8. doi: 10.1002/1439-7633(20021004)3:10<993::AID-CBIC993>3.0.CO;2-Y. Chembiochem. 2002. PMID: 12362365

8

Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.

DeVree BT, Mahoney JP, Vélez-Ruiz GA, Rasmussen SG, Kuszak AJ, Edwald E, Fung JJ, Manglik A, Masureel M, Du Y, Matt RA, Pardon E, Steyaert J, Kobilka BK, Sunahara RK. DeVree BT, et al. Nature. 2016 Jul 7;535(7610):182-6. doi: 10.1038/nature18324. Epub 2016 Jun 29. Nature. 2016. PMID: 27362234 Free PMC article.

9

A monoclonal antibody for G protein-coupled receptor crystallography.

Day PW, Rasmussen SG, Parnot C, Fung JJ, Masood A, Kobilka TS, Yao XJ, Choi HJ, Weis WI, Rohrer DK, Kobilka BK. Day PW, et al. Nat Methods. 2007 Nov;4(11):927-9. doi: 10.1038/nmeth1112. Epub 2007 Oct 21. Nat Methods. 2007. PMID: 17952087

10

Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility.

Gether U, Ballesteros JA, Seifert R, Sanders-Bush E, Weinstein H, Kobilka BK. Gether U, et al. J Biol Chem. 1997 Jan 31;272(5):2587-90. doi: 10.1074/jbc.272.5.2587. J Biol Chem. 1997. PMID: 9006889 Free article.

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