NS076919/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

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Identification of novel polyglutamine-expanded aggregation species in spinal and bulbar muscular atrophy.

Berger TR, Montie HL, Jain P, Legleiter J, Merry DE. Berger TR, et al. Brain Res. 2015 Dec 2;1628(Pt B):254-264. doi: 10.1016/j.brainres.2015.09.033. Epub 2015 Oct 8. Brain Res. 2015. PMID: 26453288 Free PMC article.

Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA.

Zboray L, Pluciennik A, Curtis D, Liu Y, Berman-Booty LD, Orr C, Kesler CT, Berger T, Gioeli D, Paschal BM, Merry DE. Zboray L, et al. Cell Rep. 2015 Dec 15;13(10):2312-23. doi: 10.1016/j.celrep.2015.11.019. Epub 2015 Dec 7. Cell Rep. 2015. PMID: 26673324 Free PMC article.

Proteasome-mediated proteolysis of the polyglutamine-expanded androgen receptor is a late event in spinal and bulbar muscular atrophy (SBMA) pathogenesis.

Heine EM, Berger TR, Pluciennik A, Orr CR, Zboray L, Merry DE. Heine EM, et al. J Biol Chem. 2015 May 15;290(20):12572-84. doi: 10.1074/jbc.M114.617894. Epub 2015 Mar 20. J Biol Chem. 2015. PMID: 25795778 Free PMC article.

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