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LC-MS/MS quantification of a neuropeptide fragment kisspeptin-10 (NSC 741805) and characterization of its decomposition product and pharmacokinetics in rats.
Liu Z, Ren C, Jones W, Chen P, Seminara SB, Chan YM, Smith NF, Covey JM, Wang J, Chan KK. Liu Z, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 May 1;926:1-8. doi: 10.1016/j.jchromb.2013.02.027. Epub 2013 Mar 4. J Chromatogr B Analyt Technol Biomed Life Sci. 2013. PMID: 23524040 Free PMC article.
Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy.
Mahfouz RZ, Jankowska A, Ebrahem Q, Gu X, Visconte V, Tabarroki A, Terse P, Covey J, Chan K, Ling Y, Engelke KJ, Sekeres MA, Tiu R, Maciejewski J, Radivoyevitch T, Saunthararajah Y. Mahfouz RZ, et al. Clin Cancer Res. 2013 Feb 15;19(4):938-48. doi: 10.1158/1078-0432.CCR-12-1722. Epub 2013 Jan 3. Clin Cancer Res. 2013. PMID: 23287564 Free PMC article.