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Page 1
Macromolecular condensation buffers intracellular water potential.
Watson JL, Seinkmane E, Styles CT, Mihut A, Krüger LK, McNally KE, Planelles-Herrero VJ, Dudek M, McCall PM, Barbiero S, Vanden Oever M, Peak-Chew SY, Porebski BT, Zeng A, Rzechorzek NM, Wong DCS, Beale AD, Stangherlin A, Riggi M, Iwasa J, Morf J, Miliotis C, Guna A, Inglis AJ, Brugués J, Voorhees RM, Chambers JE, Meng QJ, O'Neill JS, Edgar RS, Derivery E. Watson JL, et al. Nature. 2023 Nov;623(7988):842-852. doi: 10.1038/s41586-023-06626-z. Epub 2023 Oct 18. Nature. 2023. PMID: 37853127 Free PMC article.
CRYPTOCHROMES promote daily protein homeostasis.
Wong DCS, Seinkmane E, Zeng A, Stangherlin A, Rzechorzek NM, Beale AD, Day J, Reed M, Peak-Chew SY, Styles CT, Edgar RS, Putker M, O'Neill JS. Wong DCS, et al. EMBO J. 2022 Jan 4;41(1):e108883. doi: 10.15252/embj.2021108883. Epub 2021 Nov 29. EMBO J. 2022. PMID: 34842284 Free PMC article.
A daily temperature rhythm in the human brain predicts survival after brain injury.
Rzechorzek NM, Thrippleton MJ, Chappell FM, Mair G, Ercole A, Cabeleira M; CENTER-TBI High Resolution ICU (HR ICU) Sub-Study Participants and Investigators; Rhodes J, Marshall I, O'Neill JS. Rzechorzek NM, et al. Brain. 2022 Jun 30;145(6):2031-2048. doi: 10.1093/brain/awab466. Brain. 2022. PMID: 35691613 Free PMC article.
Healthy human brains have a daily heatwave.
Rzechorzek NM, O'Neill JS. Rzechorzek NM, et al. Temperature (Austin). 2023 Apr 3;10(2):155-158. doi: 10.1080/23328940.2022.2150040. Epub 2023 Jun 15. Temperature (Austin). 2023. PMID: 37325254 Free PMC article. No abstract available.
CRYPTOCHROMES confer robustness, not rhythmicity, to circadian timekeeping.
Putker M, Wong DCS, Seinkmane E, Rzechorzek NM, Zeng A, Hoyle NP, Chesham JE, Edwards MD, Feeney KA, Fischer R, Peschel N, Chen KF, Vanden Oever M, Edgar RS, Selby CP, Sancar A, O'Neill JS. Putker M, et al. EMBO J. 2021 Apr 1;40(7):e106745. doi: 10.15252/embj.2020106745. Epub 2021 Jan 25. EMBO J. 2021. PMID: 33491228 Free PMC article.