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Page 1
Neuronal enhancers are hotspots for DNA single-strand break repair.
Wu W, Hill SE, Nathan WJ, Paiano J, Callen E, Wang D, Shinoda K, van Wietmarschen N, Colón-Mercado JM, Zong D, De Pace R, Shih HY, Coon S, Parsadanian M, Pavani R, Hanzlikova H, Park S, Jung SK, McHugh PJ, Canela A, Chen C, Casellas R, Caldecott KW, Ward ME, Nussenzweig A. Wu W, et al. Nature. 2021 May;593(7859):440-444. doi: 10.1038/s41586-021-03468-5. Epub 2021 Mar 25. Nature. 2021. PMID: 33767446 Free PMC article.
XRCC1 prevents toxic PARP1 trapping during DNA base excision repair.
Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW. Demin AA, et al. Mol Cell. 2021 Jul 15;81(14):3018-3030.e5. doi: 10.1016/j.molcel.2021.05.009. Epub 2021 Jun 7. Mol Cell. 2021. PMID: 34102106 Free PMC article.
XRCC1 protein; Form and function.
Caldecott KW. Caldecott KW. DNA Repair (Amst). 2019 Sep;81:102664. doi: 10.1016/j.dnarep.2019.102664. Epub 2019 Jul 8. DNA Repair (Amst). 2019. PMID: 31324530 Review.
BRAT1 links Integrator and defective RNA processing with neurodegeneration.
Cihlarova Z, Kubovciak J, Sobol M, Krejcikova K, Sachova J, Kolar M, Stanek D, Barinka C, Yoon G, Caldecott KW, Hanzlikova H. Cihlarova Z, et al. Nat Commun. 2022 Aug 26;13(1):5026. doi: 10.1038/s41467-022-32763-6. Nat Commun. 2022. PMID: 36028512 Free PMC article.
24 results