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The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing.
Sexton JE, Desmonds T, Quick K, Taylor R, Abramowitz J, Forge A, Kros CJ, Birnbaumer L, Wood JN. Sexton JE, et al. Neurosci Lett. 2016 Jan 1;610:36-42. doi: 10.1016/j.neulet.2015.10.052. Epub 2015 Oct 28. Neurosci Lett. 2016. PMID: 26520460 Free PMC article.
Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity.
Kenyon EJ, Kirkwood NK, Kitcher SR, Goodyear RJ, Derudas M, Cantillon DM, Baxendale S, de la Vega de León A, Mahieu VN, Osgood RT, Wilson CD, Bull JC, Waddell SJ, Whitfield TT, Ward SE, Kros CJ, Richardson GP. Kenyon EJ, et al. JCI Insight. 2021 Apr 8;6(7):e145704. doi: 10.1172/jci.insight.145704. JCI Insight. 2021. PMID: 33735112 Free PMC article.
Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel.
O'Reilly M, Kirkwood NK, Kenyon EJ, Huckvale R, Cantillon DM, Waddell SJ, Ward SE, Richardson GP, Kros CJ, Derudas M. O'Reilly M, et al. J Med Chem. 2019 Jun 13;62(11):5312-5329. doi: 10.1021/acs.jmedchem.8b01325. Epub 2019 May 24. J Med Chem. 2019. PMID: 31083995 Free article.
21 results