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Page 1
Geographical migration and fitness dynamics of Streptococcus pneumoniae.
Belman S, Lefrancq N, Nzenze S, Downs S, du Plessis M, Lo SW; Global Pneumococcal Sequencing Consortium; McGee L, Madhi SA, von Gottberg A, Bentley SD, Salje H. Belman S, et al. Nature. 2024 Jul;631(8020):386-392. doi: 10.1038/s41586-024-07626-3. Epub 2024 Jul 3. Nature. 2024. PMID: 38961295 Free PMC article.
Genomic epidemiology of Streptococcus pneumoniae serotype 16F lineages.
Mokaya J, Mellor KC, Murray GGR, Kalizang'oma A, Lekhuleni C, Zar HJ, Nicol MP, McGee L, Bentley SD, Lo SW, Dube F. Mokaya J, et al. Among authors: lekhuleni c. Microb Genom. 2023 Nov;9(11):001123. doi: 10.1099/mgen.0.001123. Microb Genom. 2023. PMID: 37917136 Free PMC article.
Meningitis-associated pneumococcal serotype 8, ST 53, strain is hypervirulent in a rat model and has non-haemolytic pneumolysin which can be attenuated by liposomes.
Müller A, Lekhuleni C, Hupp S, du Plessis M, Holivololona L, Babiychuk E, Leib SL, Grandgirard D, Iliev AI, von Gottberg A, Hathaway LJ. Müller A, et al. Among authors: lekhuleni c. Front Cell Infect Microbiol. 2023 Jan 6;12:1106063. doi: 10.3389/fcimb.2022.1106063. eCollection 2022. Front Cell Infect Microbiol. 2023. PMID: 36683678 Free PMC article.
Evidence of virulence and antimicrobial resistance in Streptococcus pneumoniae serotype 16F lineages.
Mokaya J, Mellor KC, Murray GGR, Kalizang'oma A, Lekhuleni C, Zar HJ, Nicol MP, McGee L, Bentley SD, Lo SW, Dube F; Global Pneumococcal Sequencing Consortium. Mokaya J, et al. Among authors: lekhuleni c. bioRxiv [Preprint]. 2023 Aug 28:2023.08.25.554804. doi: 10.1101/2023.08.25.554804. bioRxiv. 2023. Update in: Microb Genom. 2023 Nov;9(11). doi: 10.1099/mgen.0.001123. PMID: 37693504 Free PMC article. Updated. Preprint.
Impact of pneumococcal conjugate vaccines on invasive pneumococcal disease-causing lineages among South African children.
Lekhuleni C, Ndlangisa K, Gladstone RA, Chochua S, Metcalf BJ, Li Y, Kleynhans J, de Gouveia L, Hazelhurst S, Ferreira ADS, Skosana H, Walaza S, Quan V, Meiring S, Hawkins PA, McGee L, Bentley SD, Cohen C, Lo SW, von Gottberg A, du Plessis M. Lekhuleni C, et al. Nat Commun. 2024 Sep 27;15(1):8401. doi: 10.1038/s41467-024-52459-3. Nat Commun. 2024. PMID: 39333488 Free PMC article.