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A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction.
Schneider C, Hilbert J, Genevaux F, Höfer S, Krauß L, Schicktanz F, Contreras CT, Jansari S, Papargyriou A, Richter T, Alfayomy AM, Falcomatà C, Schneeweis C, Orben F, Öllinger R, Wegwitz F, Boshnakovska A, Rehling P, Müller D, Ströbel P, Ellenrieder V, Conradi L, Hessmann E, Ghadimi M, Grade M, Wirth M, Steiger K, Rad R, Kuster B, Sippl W, Reichert M, Saur D, Schneider G. Schneider C, et al. Adv Sci (Weinh). 2024 Aug;11(31):e2307695. doi: 10.1002/advs.202307695. Epub 2024 Jun 17. Adv Sci (Weinh). 2024. PMID: 38885414 Free PMC article.
The Microbiome in PDAC-Vantage Point for Future Therapies?
Pfisterer N, Lingens C, Heuer C, Dang L, Neesse A, Ammer-Herrmenau C. Pfisterer N, et al. Cancers (Basel). 2022 Dec 2;14(23):5974. doi: 10.3390/cancers14235974. Cancers (Basel). 2022. PMID: 36497456 Free PMC article. Review.
KRASG 12C-inhibitor-based combination therapies for pancreatic cancer: insights from drug screening.
Tapia Contreras C, Falke JD, Seifert DM, Schneider C, Krauß L, Fang X, Müller D, Demirdizen E, Spitzner M, De Oliveira T, Schneeweis C, Gaedcke J, Kaulfuß S, Mirzakhani K, Wollnik B, Conrads K, Beißbarth T, Salinas G, Hügel J, Beyer N, Rheinländer S, Sax U, Wirth M, Conradi LC, Reichert M, Ellenrieder V, Ströbel P, Ghadimi M, Grade M, Saur D, Hessmann E, Schneider G. Tapia Contreras C, et al. Mol Oncol. 2024 Sep 10. doi: 10.1002/1878-0261.13725. Online ahead of print. Mol Oncol. 2024. PMID: 39253995 Free article.
TP53-Status-Dependent Oncogenic EZH2 Activity in Pancreatic Cancer.
Versemann L, Patil S, Steuber B, Zhang Z, Kopp W, Krawczyk HE, Kaulfuß S, Wollnik B, Ströbel P, Neesse A, Singh SK, Ellenrieder V, Hessmann E. Versemann L, et al. Cancers (Basel). 2022 Jul 15;14(14):3451. doi: 10.3390/cancers14143451. Cancers (Basel). 2022. PMID: 35884510 Free PMC article.
Chromatin-Independent Interplay of NFATc1 and EZH2 in Pancreatic Cancer.
Patil S, Forster T, Reutlinger K, Kopp W, Versemann L, Spitalieri J, Gaedcke J, Ströbel P, Singh SK, Ellenrieder V, Neesse A, Hessmann E. Patil S, et al. Cells. 2021 Dec 8;10(12):3463. doi: 10.3390/cells10123463. Cells. 2021. PMID: 34943970 Free PMC article.
Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo.
De Oliveira T, Goldhardt T, Edelmann M, Rogge T, Rauch K, Kyuchukov ND, Menck K, Bleckmann A, Kalucka J, Khan S, Gaedcke J, Haubrock M, Beissbarth T, Bohnenberger H, Planque M, Fendt SM, Ackermann L, Ghadimi M, Conradi LC. De Oliveira T, et al. Cancers (Basel). 2021 Feb 28;13(5):1011. doi: 10.3390/cancers13051011. Cancers (Basel). 2021. PMID: 33671096 Free PMC article.
Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response in pancreatic cancer.
Klein L, Tu M, Krebs N, Urbach L, Grimm D, Latif MU, Penz F, Blandau A, Wu X, Samuel RD, Küffer S, Wegwitz F, Chan N, Aliar K, Vyas F, Kishore U, Hessmann E, Trumpp A, Espinet E, Papantonis A, Khokha R, Ellenrieder V, Grünwald BT, Singh SK. Klein L, et al. Nat Commun. 2025 Jan 6;16(1):335. doi: 10.1038/s41467-024-55330-7. Nat Commun. 2025. PMID: 39762215