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Page 1
Genetic, dietary, and sex-specific regulation of hepatic ceramides and the relationship between hepatic ceramides and IR.
Norheim F, Bjellaas T, Hui ST, Chella Krishnan K, Lee J, Gupta S, Pan C, Hasin-Brumshtein Y, Parks BW, Li DY, Bui HH, Mosier M, Wu Y, Huertas-Vazquez A, Hazen SL, Gundersen TE, Mehrabian M, Tang WHW, Hevener AL, Drevon CA, Lusis AJ. Norheim F, et al. J Lipid Res. 2018 Jul;59(7):1164-1174. doi: 10.1194/jlr.M081398. Epub 2018 May 8. J Lipid Res. 2018. PMID: 29739864 Free PMC article.
Genetic architecture of insulin resistance in the mouse.
Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Parks BW, et al. Cell Metab. 2015 Feb 3;21(2):334-347. doi: 10.1016/j.cmet.2015.01.002. Cell Metab. 2015. PMID: 25651185 Free PMC article.
Integrating Mouse and Human Genetic Data to Move beyond GWAS and Identify Causal Genes in Cholesterol Metabolism.
Li Z, Votava JA, Zajac GJM, Nguyen JN, Leyva Jaimes FB, Ly SM, Brinkman JA, De Giorgi M, Kaul S, Green CL, St Clair SL, Belisle SL, Rios JM, Nelson DW, Sorci-Thomas MG, Lagor WR, Lamming DW, Eric Yen CL, Parks BW. Li Z, et al. Cell Metab. 2020 Apr 7;31(4):741-754.e5. doi: 10.1016/j.cmet.2020.02.015. Epub 2020 Mar 19. Cell Metab. 2020. PMID: 32197071 Free PMC article.
Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression.
Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. Drew BG, et al. J Biol Chem. 2015 Feb 27;290(9):5566-81. doi: 10.1074/jbc.M114.606459. Epub 2014 Dec 2. J Biol Chem. 2015. PMID: 25468909 Free PMC article.
The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice.
Zhou X, Crow AL, Hartiala J, Spindler TJ, Ghazalpour A, Barsky LW, Bennett BJ, Parks BW, Eskin E, Jain R, Epstein JA, Lusis AJ, Adams GB, Allayee H. Zhou X, et al. Stem Cell Reports. 2015 Jul 14;5(1):125-38. doi: 10.1016/j.stemcr.2015.05.008. Epub 2015 Jun 4. Stem Cell Reports. 2015. PMID: 26050929 Free PMC article.
Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females.
Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. Ribas V, et al. Sci Transl Med. 2016 Apr 13;8(334):334ra54. doi: 10.1126/scitranslmed.aad3815. Sci Transl Med. 2016. PMID: 27075628 Free PMC article.