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Page 1
Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression.
Francescone R, Barbosa Vendramini-Costa D, Franco-Barraza J, Wagner J, Muir A, Lau AN, Gabitova L, Pazina T, Gupta S, Luong T, Rollins D, Malik R, Thapa RJ, Restifo D, Zhou Y, Cai KQ, Hensley HH, Tan Y, Kruger WD, Devarajan K, Balachandran S, Klein-Szanto AJ, Wang H, El-Deiry WS, Vander Heiden MG, Peri S, Campbell KS, Astsaturov I, Cukierman E. Francescone R, et al. Cancer Discov. 2021 Feb;11(2):446-479. doi: 10.1158/2159-8290.CD-20-0775. Epub 2020 Oct 30. Cancer Discov. 2021. PMID: 33127842 Free PMC article.
Cancer tissue of origin constrains the growth and metabolism of metastases.
Sivanand S, Gultekin Y, Winter PS, Vermeulen SY, Tchourine KM, Abbott KL, Danai LV, Gourgue F, Do BT, Crowder K, Kunchok T, Lau AN, Darnell AM, Jefferson A, Morita S, Duda DG, Aguirre AJ, Wolpin BM, Henning N, Spanoudaki V, Maiorino L, Irvine DJ, Yilmaz OH, Lewis CA, Vitkup D, Shalek AK, Vander Heiden MG. Sivanand S, et al. Nat Metab. 2024 Sep;6(9):1668-1681. doi: 10.1038/s42255-024-01105-9. Epub 2024 Aug 19. Nat Metab. 2024. PMID: 39160333
Effects of aging on glucose and lipid metabolism in mice.
Lien EC, Vu N, Westermark AM, Danai LV, Lau AN, Gültekin Y, Kukurugya MA, Bennett BD, Vander Heiden MG. Lien EC, et al. bioRxiv [Preprint]. 2023 Dec 18:2023.12.17.572088. doi: 10.1101/2023.12.17.572088. bioRxiv. 2023. PMID: 38187759 Free PMC article. Preprint.
Putting the K+ in K+aloric Restriction.
Lien EC, Lau AN, Vander Heiden MG. Lien EC, et al. Immunity. 2019 May 21;50(5):1129-1131. doi: 10.1016/j.immuni.2019.04.016. Immunity. 2019. PMID: 31117009 Free article.
Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma.
Lau AN, Li Z, Danai LV, Westermark AM, Darnell AM, Ferreira R, Gocheva V, Sivanand S, Lien EC, Sapp KM, Mayers JR, Biffi G, Chin CR, Davidson SM, Tuveson DA, Jacks T, Matheson NJ, Yilmaz O, Vander Heiden MG. Lau AN, et al. Elife. 2020 Jul 10;9:e56782. doi: 10.7554/eLife.56782. Elife. 2020. PMID: 32648540 Free PMC article.
Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance.
Dalin S, Sullivan MR, Lau AN, Grauman-Boss B, Mueller HS, Kreidl E, Fenoglio S, Luengo A, Lees JA, Vander Heiden MG, Lauffenburger DA, Hemann MT. Dalin S, et al. Cancer Res. 2019 Nov 15;79(22):5723-5733. doi: 10.1158/0008-5472.CAN-19-0960. Epub 2019 Sep 4. Cancer Res. 2019. PMID: 31484670 Free PMC article.
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