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Page 1
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.
Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS. Gilbert LA, et al. Cell. 2014 Oct 23;159(3):647-61. doi: 10.1016/j.cell.2014.09.029. Epub 2014 Oct 9. Cell. 2014. PMID: 25307932 Free PMC article.
Mapping the Genetic Landscape of Human Cells.
Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA. Horlbeck MA, et al. Cell. 2018 Aug 9;174(4):953-967.e22. doi: 10.1016/j.cell.2018.06.010. Epub 2018 Jul 19. Cell. 2018. PMID: 30033366 Free PMC article.
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids.
Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, Farese RV Jr. Piccolis M, et al. Mol Cell. 2019 Apr 4;74(1):32-44.e8. doi: 10.1016/j.molcel.2019.01.036. Epub 2019 Mar 4. Mol Cell. 2019. PMID: 30846318 Free PMC article.
Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent.
Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. Jost M, et al. Mol Cell. 2020 Jul 2;79(1):191-198.e3. doi: 10.1016/j.molcel.2020.06.008. Mol Cell. 2020. PMID: 32619469 Free PMC article.
CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma.
Ramkumar P, Abarientos AB, Tian R, Seyler M, Leong JT, Chen M, Choudhry P, Hechler T, Shah N, Wong SW, Martin TG, Wolf JL, Roybal KT, Pahl A, Taunton J, Wiita AP, Kampmann M. Ramkumar P, et al. Blood Adv. 2020 Jul 14;4(13):2899-2911. doi: 10.1182/bloodadvances.2019001346. Blood Adv. 2020. PMID: 32589729 Free PMC article.
Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification.
Deans RM, Morgens DW, Ökesli A, Pillay S, Horlbeck MA, Kampmann M, Gilbert LA, Li A, Mateo R, Smith M, Glenn JS, Carette JE, Khosla C, Bassik MC. Deans RM, et al. Nat Chem Biol. 2016 May;12(5):361-6. doi: 10.1038/nchembio.2050. Epub 2016 Mar 28. Nat Chem Biol. 2016. PMID: 27018887 Free PMC article.
Next-generation libraries for robust RNA interference-based genome-wide screens.
Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS. Kampmann M, et al. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):E3384-91. doi: 10.1073/pnas.1508821112. Epub 2015 Jun 15. Proc Natl Acad Sci U S A. 2015. PMID: 26080438 Free PMC article.
20 results