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Page 1
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.
Fritsche LG, Igl W, Bailey JN, Grassmann F, Sengupta S, Bragg-Gresham JL, Burdon KP, Hebbring SJ, Wen C, Gorski M, Kim IK, Cho D, Zack D, Souied E, Scholl HP, Bala E, Lee KE, Hunter DJ, Sardell RJ, Mitchell P, Merriam JE, Cipriani V, Hoffman JD, Schick T, Lechanteur YT, Guymer RH, Johnson MP, Jiang Y, Stanton CM, Buitendijk GH, Zhan X, Kwong AM, Boleda A, Brooks M, Gieser L, Ratnapriya R, Branham KE, Foerster JR, Heckenlively JR, Othman MI, Vote BJ, Liang HH, Souzeau E, McAllister IL, Isaacs T, Hall J, Lake S, Mackey DA, Constable IJ, Craig JE, Kitchner TE, Yang Z, Su Z, Luo H, Chen D, Ouyang H, Flagg K, Lin D, Mao G, Ferreyra H, Stark K, von Strachwitz CN, Wolf A, Brandl C, Rudolph G, Olden M, Morrison MA, Morgan DJ, Schu M, Ahn J, Silvestri G, Tsironi EE, Park KH, Farrer LA, Orlin A, Brucker A, Li M, Curcio CA, Mohand-Saïd S, Sahel JA, Audo I, Benchaboune M, Cree AJ, Rennie CA, Goverdhan SV, Grunin M, Hagbi-Levi S, Campochiaro P, Katsanis N, Holz FG, Blond F, Blanché H, Deleuze JF, Igo RP Jr, Truitt B, Peachey NS, Meuer SM, Myers CE, Moore EL, Klein R, Hauser MA, Postel EA, Courtenay MD, Schwartz SG, Kovach JL, Scott WK, Liew G, Tan AG, Gopinath B, Merriam JC, Smith RT, Khan JC,… See abstract for full author list ➔ Fritsche LG, et al. Nat Genet. 2016 Feb;48(2):134-43. doi: 10.1038/ng.3448. Epub 2015 Dec 21. Nat Genet. 2016. PMID: 26691988 Free PMC article.
Genomic and Phenomic Research in the 21st Century.
Hebbring S. Hebbring S. Trends Genet. 2019 Jan;35(1):29-41. doi: 10.1016/j.tig.2018.09.007. Epub 2018 Oct 17. Trends Genet. 2019. PMID: 30342790 Free PMC article. Review.
Estimating the efficacy of pharmacogenomics over a lifetime.
Ye Z, Mayer J, Leary EJ, Kitchner T, Dart RA, Brilliant MH, Hebbring SJ. Ye Z, et al. Front Med (Lausanne). 2023 Oct 31;10:1006743. doi: 10.3389/fmed.2023.1006743. eCollection 2023. Front Med (Lausanne). 2023. PMID: 38020121 Free PMC article.
The phenotypic legacy of admixture between modern humans and Neandertals.
Simonti CN, Vernot B, Bastarache L, Bottinger E, Carrell DS, Chisholm RL, Crosslin DR, Hebbring SJ, Jarvik GP, Kullo IJ, Li R, Pathak J, Ritchie MD, Roden DM, Verma SS, Tromp G, Prato JD, Bush WS, Akey JM, Denny JC, Capra JA. Simonti CN, et al. Science. 2016 Feb 12;351(6274):737-41. doi: 10.1126/science.aad2149. Science. 2016. PMID: 26912863 Free PMC article.
Phenome-wide association studies (PheWASs) for functional variants.
Ye Z, Mayer J, Ivacic L, Zhou Z, He M, Schrodi SJ, Page D, Brilliant MH, Hebbring SJ. Ye Z, et al. Eur J Hum Genet. 2015 Apr;23(4):523-9. doi: 10.1038/ejhg.2014.123. Epub 2014 Jul 30. Eur J Hum Genet. 2015. PMID: 25074467 Free PMC article.
RNA-Binding Protein IGF2BP1 in Cutaneous Squamous Cell Carcinoma.
Kim T, Havighurst T, Kim K, Hebbring SJ, Ye Z, Aylward J, Keles S, Xu YG, Spiegelman VS. Kim T, et al. J Invest Dermatol. 2017 Mar;137(3):772-775. doi: 10.1016/j.jid.2016.10.042. Epub 2016 Nov 14. J Invest Dermatol. 2017. PMID: 27856289 Free PMC article. No abstract available.
Identifying genetically driven clinical phenotypes using linear mixed models.
Mosley JD, Witte JS, Larkin EK, Bastarache L, Shaffer CM, Karnes JH, Stein CM, Phillips E, Hebbring SJ, Brilliant MH, Mayer J, Ye Z, Roden DM, Denny JC. Mosley JD, et al. Nat Commun. 2016 Apr 25;7:11433. doi: 10.1038/ncomms11433. Nat Commun. 2016. PMID: 27109359 Free PMC article.
19 results