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2019 2
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2024 7

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29 results

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Page 1
Macrophage-derived netrin-1 drives adrenergic nerve-associated lung fibrosis.
Gao R, Peng X, Perry C, Sun H, Ntokou A, Ryu C, Gomez JL, Reeves BC, Walia A, Kaminski N, Neumark N, Ishikawa G, Black KE, Hariri LP, Moore MW, Gulati M, Homer RJ, Greif DM, Eltzschig HK, Herzog EL. Gao R, et al. J Clin Invest. 2021 Jan 4;131(1):e136542. doi: 10.1172/JCI136542. J Clin Invest. 2021. PMID: 33393489 Free PMC article.
Single-cell profiling reveals immune aberrations in progressive idiopathic pulmonary fibrosis.
Unterman A, Zhao AY, Neumark N, Schupp JC, Ahangari F, Cosme C Jr, Sharma P, Flint J, Stein Y, Ryu C, Ishikawa G, Sumida TS, Gomez JL, Herazo-Maya J, Dela Cruz CS, Herzog EL, Kaminski N. Unterman A, et al. medRxiv [Preprint]. 2023 Apr 29:2023.04.29.23289296. doi: 10.1101/2023.04.29.23289296. medRxiv. 2023. Update in: Am J Respir Crit Care Med. 2024 Aug 15;210(4):484-496. doi: 10.1164/rccm.202306-0979OC PMID: 37163015 Free PMC article. Updated. Preprint.
microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis.
Ahangari F, Price NL, Malik S, Chioccioli M, Bärnthaler T, Adams TS, Kim J, Pradeep SP, Ding S, Cosmos C Jr, Rose KS, McDonough JE, Aurelien NR, Ibarra G, Omote N, Schupp JC, DeIuliis G, Villalba Nunez JA, Sharma L, Ryu C, Dela Cruz CS, Liu X, Prasse A, Rosas I, Bahal R, Fernández-Hernando C, Kaminski N. Ahangari F, et al. JCI Insight. 2023 Feb 22;8(4):e158100. doi: 10.1172/jci.insight.158100. JCI Insight. 2023. PMID: 36626225 Free PMC article.
Single-Cell Profiling Reveals Immune Aberrations in Progressive Idiopathic Pulmonary Fibrosis.
Unterman A, Zhao AY, Neumark N, Schupp JC, Ahangari F, Cosme C Jr, Sharma P, Flint J, Stein Y, Ryu C, Ishikawa G, Sumida TS, Gomez JL, Herazo-Maya JD, Dela Cruz CS, Herzog EL, Kaminski N. Unterman A, et al. Am J Respir Crit Care Med. 2024 Aug 15;210(4):484-496. doi: 10.1164/rccm.202306-0979OC. Am J Respir Crit Care Med. 2024. PMID: 38717443
TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance.
Çakan E, Ah Kioon MD, Garcia-Carmona Y, Glauzy S, Oliver D, Yamakawa N, Vega Loza A, Du Y, Schickel JN, Boeckers JM, Yang C, Baldo A, Ivashkiv LB, Young RM, Staudt LM, Moody KL, Nündel K, Marshak-Rothstein A, van der Made CI, Hoischen A, Hayward A, Rossato M, Radstake TRDJ, Cunningham-Rundles C, Ryu C, Herzog EL, Barrat FJ, Meffre E. Çakan E, et al. J Exp Med. 2023 Dec 4;220(12):e20230944. doi: 10.1084/jem.20230944. Epub 2023 Sep 29. J Exp Med. 2023. PMID: 37773045 Free PMC article.
Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis.
Damsky W, Wang A, Kim DJ, Young BD, Singh K, Murphy MJ, Daccache J, Clark A, Ayasun R, Ryu C, McGeary MK, Odell ID, Fazzone-Chettiar R, Pucar D, Homer R, Gulati M, Miller EJ, Bosenberg M, Flavell RA, King B. Damsky W, et al. Nat Commun. 2022 Jun 6;13(1):3140. doi: 10.1038/s41467-022-30615-x. Nat Commun. 2022. PMID: 35668129 Free PMC article. Clinical Trial.
Single-Cell Analysis Reveals Novel Immune Perturbations in Fibrotic Hypersensitivity Pneumonitis.
Zhao AY, Unterman A, Abu Hussein NS, Sharma P, Nikola F, Flint J, Yan X, Adams TS, Justet A, Sumida TS, Zhao J, Schupp JC, Raredon MSB, Ahangari F, Deluliis G, Zhang Y, Buendia-Roldan I, Adegunsoye A, Sperling AI, Prasse A, Ryu C, Herzog E, Selman M, Pardo A, Kaminski N. Zhao AY, et al. Am J Respir Crit Care Med. 2024 Nov 15;210(10):1252-1266. doi: 10.1164/rccm.202401-0078OC. Am J Respir Crit Care Med. 2024. PMID: 38924775 Free PMC article.
Toll-like Receptor 9 Inhibition Mitigates Fibroproliferative Responses in Translational Models of Pulmonary Fibrosis.
Trujillo G, Regueiro-Ren A, Liu C, Hu B, Sun Y, Ahangari F, Fiorini V, Ishikawa G, Al Jumaily K, Khoury J, McGovern J, Lee CJ, Peng XY, Pivarnik T, Sun H, Walia A, Woo S, Yu S, Antin-Ozerkis DE, Sauler M, Kaminski N, Herzog EL, Ryu C. Trujillo G, et al. Am J Respir Crit Care Med. 2024 Aug 27. doi: 10.1164/rccm.202401-0065OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 39189851
Alveolar Vascular Remodeling in Nonspecific Interstitial Pneumonia: Replacement of Normal Lung Capillaries with COL15A1-Positive Endothelial Cells.
Schupp JC, Manning EP, Chioccioli M, Kamp JC, Christian L, Ryu C, Herzog E, Kühnel MP, Prasse A, Kaminski N, Jonigk DD, Homer RJ; Yale-MHH-MGH Study Group. Schupp JC, et al. Am J Respir Crit Care Med. 2023 Oct 1;208(7):819-822. doi: 10.1164/rccm.202303-0544LE. Am J Respir Crit Care Med. 2023. PMID: 37552025 Free PMC article. No abstract available.
29 results