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A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.
Montoro DT, Haber AL, Biton M, Vinarsky V, Lin B, Birket SE, Yuan F, Chen S, Leung HM, Villoria J, Rogel N, Burgin G, Tsankov AM, Waghray A, Slyper M, Waldman J, Nguyen L, Dionne D, Rozenblatt-Rosen O, Tata PR, Mou H, Shivaraju M, Bihler H, Mense M, Tearney GJ, Rowe SM, Engelhardt JF, Regev A, Rajagopal J. Montoro DT, et al. Nature. 2018 Aug;560(7718):319-324. doi: 10.1038/s41586-018-0393-7. Epub 2018 Aug 1. Nature. 2018. PMID: 30069044 Free PMC article.
Ivacaftor partially corrects airway inflammation in a humanized G551D rat.
Green M, Lindgren N, Henderson A, Keith JD, Oden AM, Birket SE. Green M, et al. Am J Physiol Lung Cell Mol Physiol. 2021 Jun 1;320(6):L1093-L1100. doi: 10.1152/ajplung.00082.2021. Epub 2021 Apr 7. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33825507 Free PMC article.
Klotho Inhibits Interleukin-8 Secretion from Cystic Fibrosis Airway Epithelia.
Krick S, Baumlin N, Aller SP, Aguiar C, Grabner A, Sailland J, Mendes E, Schmid A, Qi L, David NV, Geraghty P, King G, Birket SE, Rowe SM, Faul C, Salathe M. Krick S, et al. Sci Rep. 2017 Oct 30;7(1):14388. doi: 10.1038/s41598-017-14811-0. Sci Rep. 2017. PMID: 29085059 Free PMC article.
Development of an airway mucus defect in the cystic fibrosis rat.
Birket SE, Davis JM, Fernandez CM, Tuggle KL, Oden AM, Chu KK, Tearney GJ, Fanucchi MV, Sorscher EJ, Rowe SM. Birket SE, et al. JCI Insight. 2018 Jan 11;3(1):e97199. doi: 10.1172/jci.insight.97199. eCollection 2018 Jan 11. JCI Insight. 2018. PMID: 29321377 Free PMC article.
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