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Pre-assembled tau filaments phosphorylated by GSK-3b form large tangle-like structures.
Neurobiol Dis. 2008 Sep;31(3):368-77. doi: 10.1016/j.nbd.2008.05.011. Epub 2008 Jul 16.
Neurobiol Dis. 2008.
PMID: 18588978
Free PMC article.
Pseudohyperphosphorylation causing AD-like changes in tau has significant effects on its polymerization.
Sun Q, Gamblin TC.
Sun Q, et al.
Biochemistry. 2009 Jun 30;48(25):6002-11. doi: 10.1021/bi900602h.
Biochemistry. 2009.
PMID: 19459590
Free PMC article.
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GSK-3beta phosphorylation of functionally distinct tau isoforms has differential, but mild effects.
Voss K, Gamblin TC.
Voss K, et al.
Mol Neurodegener. 2009 May 2;4:18. doi: 10.1186/1750-1326-4-18.
Mol Neurodegener. 2009.
PMID: 19409104
Free PMC article.
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