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Year Number of Results
2010 2
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2017 2
2020 1
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11 results

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Page 1
Design and Development of IKZF2 and CK1α Dual Degraders.
Miyamoto DK, Curnutt NM, Park SM, Stavropoulos A, Kharas MG, Woo CM. Miyamoto DK, et al. J Med Chem. 2023 Dec 28;66(24):16953-16979. doi: 10.1021/acs.jmedchem.3c01736. Epub 2023 Dec 12. J Med Chem. 2023. PMID: 38085607
Transcriptional control of CBX5 by the RNA binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia.
Prieto C, Nguyen DTT, Liu Z, Wheat J, Perez A, Gourkanti S, Chou T, Barin E, Velleca A, Rohwetter T, Chow A, Taggart J, Savino AM, Hoskova K, Dhodapkar M, Schurer A, Barlowe TS, Vu LP, Leslie C, Steidl U, Rabadan R, Kharas MG. Prieto C, et al. Nat Cancer. 2021 Jul;2:741-757. doi: 10.1038/s43018-021-00220-w. Epub 2021 Jul 5. Nat Cancer. 2021. PMID: 34458856 Free PMC article.
RNA Regulators in Leukemia and Lymphoma.
Prieto C, Kharas MG. Prieto C, et al. Cold Spring Harb Perspect Med. 2020 May 1;10(5):a034967. doi: 10.1101/cshperspect.a034967. Cold Spring Harb Perspect Med. 2020. PMID: 31615866 Free PMC article. Review.
Stem Cells, Cancer, and MUSASHI in Blood and Guts.
Kharas MG, Lengner CJ. Kharas MG, et al. Trends Cancer. 2017 May;3(5):347-356. doi: 10.1016/j.trecan.2017.03.007. Epub 2017 Apr 8. Trends Cancer. 2017. PMID: 28718412 Free PMC article. Review.
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs.
Park SM, Deering RP, Lu Y, Tivnan P, Lianoglou S, Al-Shahrour F, Ebert BL, Hacohen N, Leslie C, Daley GQ, Lengner CJ, Kharas MG. Park SM, et al. J Exp Med. 2014 Jan 13;211(1):71-87. doi: 10.1084/jem.20130736. Epub 2014 Jan 6. J Exp Med. 2014. PMID: 24395885 Free PMC article.
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia.
Kharas MG, Lengner CJ, Al-Shahrour F, Bullinger L, Ball B, Zaidi S, Morgan K, Tam W, Paktinat M, Okabe R, Gozo M, Einhorn W, Lane SW, Scholl C, Fröhling S, Fleming M, Ebert BL, Gilliland DG, Jaenisch R, Daley GQ. Kharas MG, et al. Nat Med. 2010 Aug;16(8):903-8. doi: 10.1038/nm.2187. Epub 2010 Jul 8. Nat Med. 2010. PMID: 20616797 Free PMC article.
Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program.
Park SM, Gönen M, Vu L, Minuesa G, Tivnan P, Barlowe TS, Taggart J, Lu Y, Deering RP, Hacohen N, Figueroa ME, Paietta E, Fernandez HF, Tallman MS, Melnick A, Levine R, Leslie C, Lengner CJ, Kharas MG. Park SM, et al. J Clin Invest. 2015 Mar 2;125(3):1286-98. doi: 10.1172/JCI78440. Epub 2015 Feb 9. J Clin Invest. 2015. PMID: 25664853 Free PMC article.
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells.
Vu LP, Prieto C, Amin EM, Chhangawala S, Krivtsov A, Calvo-Vidal MN, Chou T, Chow A, Minuesa G, Park SM, Barlowe TS, Taggart J, Tivnan P, Deering RP, Chu LP, Kwon JA, Meydan C, Perales-Paton J, Arshi A, Gönen M, Famulare C, Patel M, Paietta E, Tallman MS, Lu Y, Glass J, Garret-Bakelman FE, Melnick A, Levine R, Al-Shahrour F, Järås M, Hacohen N, Hwang A, Garippa R, Lengner CJ, Armstrong SA, Cerchietti L, Cowley GS, Root D, Doench J, Leslie C, Ebert BL, Kharas MG. Vu LP, et al. Nat Genet. 2017 Jun;49(6):866-875. doi: 10.1038/ng.3854. Epub 2017 Apr 24. Nat Genet. 2017. PMID: 28436985 Free PMC article.
11 results