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Observing inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution.
Marx SK, Mickolajczyk KJ, Craig JM, Thomas CA, Pfeffer AM, Abell SJ, Carrasco JD, Franzi MC, Huang JR, Kim HC, Brinkerhoff H, Kapoor TM, Gundlach JH, Laszlo AH. Marx SK, et al. Nucleic Acids Res. 2023 Sep 22;51(17):9266-9278. doi: 10.1093/nar/gkad660. Nucleic Acids Res. 2023. PMID: 37560916 Free PMC article.
Inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution.
Marx SK, Mickolajczyk KJ, Craig JM, Thomas CA, Pfeffer AM, Abell SJ, Carrasco JD, Franzi MC, Huang JR, Kim HC, Brinkerhoff HD, Kapoor TM, Gundlach JH, Laszlo AH. Marx SK, et al. bioRxiv [Preprint]. 2022 Oct 8:2022.10.07.511351. doi: 10.1101/2022.10.07.511351. bioRxiv. 2022. Update in: Nucleic Acids Res. 2023 Sep 22;51(17):9266-9278. doi: 10.1093/nar/gkad660 PMID: 36238723 Free PMC article. Updated. Preprint.
Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Santarossa CC, Mickolajczyk KJ, Steinman JB, Urnavicius L, Chen N, Hirata Y, Fukase Y, Coudray N, Ekiert DC, Bhabha G, Kapoor TM. Santarossa CC, et al. Cell Chem Biol. 2021 Oct 21;28(10):1460-1473.e15. doi: 10.1016/j.chembiol.2021.04.024. Epub 2021 May 19. Cell Chem Biol. 2021. PMID: 34015309 Free PMC article.