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Transcriptomic and proteomic studies suggest the establishment of advanced zonation-like profiles in human-induced pluripotent stem cell-derived liver sinusoidal endothelial cells and carboxypeptidase M-positive liver progenitor cells cocultured in a fluidic microenvironment.
Hepatol Res. 2023 Jul;53(7):661-674. doi: 10.1111/hepr.13893. Epub 2023 Apr 2.
Hepatol Res. 2023.
PMID: 36866738
Palmitic Acid Induced a Dedifferentiation Profile at the Transcriptome Level: A Collagen Synthesis but no Triglyceride Accumulation in Hepatocyte-Like Cells Derived From Human-Induced Pluripotent Stem Cells Cultivated Inside Organ on a Chip.
Wang H, Danoy M, Gong Y, Utami T, Arakawa H, Kato Y, Nishikawa M, Sakai Y, Leclerc E.
Wang H, et al.
J Appl Toxicol. 2024 Nov 6. doi: 10.1002/jat.4714. Online ahead of print.
J Appl Toxicol. 2024.
PMID: 39506029
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