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Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer's disease.
Ocañas SR, Pham KD, Cox JEJ, Keck AW, Ko S, Ampadu FA, Porter HL, Ansere VA, Kulpa A, Kellogg CM, Machalinski AH, Thomas MA, Wright Z, Chucair-Elliott AJ, Freeman WM. Ocañas SR, et al. J Neuroinflammation. 2023 Aug 16;20(1):188. doi: 10.1186/s12974-023-02870-2. J Neuroinflammation. 2023. PMID: 37587511 Free PMC article.
Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis.
Bhaskaran S, Kumar G, Thadathil N, Piekarz KM, Mohammed S, Lopez SD, Qaisar R, Walton D, Brown JL, Murphy A, Smith N, Saunders D, Beckstead MJ, Plafker S, Lewis TL Jr, Towner R, Deepa SS, Richardson A, Axtell RC, Van Remmen H. Bhaskaran S, et al. Redox Biol. 2023 Feb;59:102550. doi: 10.1016/j.redox.2022.102550. Epub 2022 Nov 26. Redox Biol. 2023. PMID: 36470129 Free PMC article.
Translatomic response of retinal Müller glia to acute and chronic stress.
Chucair-Elliott AJ, Ocañas SR, Pham K, Van Der Veldt M, Cheyney A, Stanford D, Gurley J, Elliott MH, Freeman WM. Chucair-Elliott AJ, et al. Neurobiol Dis. 2022 Dec;175:105931. doi: 10.1016/j.nbd.2022.105931. Epub 2022 Nov 22. Neurobiol Dis. 2022. PMID: 36423879 Free PMC article.
Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer's disease.
Ocañas SR, Pham KD, Cox JEJ, Keck AW, Ko S, Ampadu FA, Porter HL, Ansere VA, Kulpa A, Kellogg CM, Machalinski AH, Chucair-Elliott AJ, Freeman WM. Ocañas SR, et al. bioRxiv [Preprint]. 2023 Jun 1:2023.03.07.531562. doi: 10.1101/2023.03.07.531562. bioRxiv. 2023. Update in: J Neuroinflammation. 2023 Aug 16;20(1):188. doi: 10.1186/s12974-023-02870-2. PMID: 36945656 Free PMC article. Updated. Preprint.
Senolytic treatment reduces cell senescence and necroptosis in Sod1 knockout mice that is associated with reduced inflammation and hepatocellular carcinoma.
Thadathil N, Selvarani R, Mohammed S, Nicklas EH, Tran AL, Kamal M, Luo W, Brown JL, Lawrence MM, Borowik AK, Miller BF, Van Remmen H, Richardson A, Deepa SS. Thadathil N, et al. Aging Cell. 2022 Aug;21(8):e13676. doi: 10.1111/acel.13676. Epub 2022 Jul 23. Aging Cell. 2022. PMID: 35869934 Free PMC article.
23 results