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Rap1b in smooth muscle and endothelium is required for maintenance of vascular tone and normal blood pressure.
Lakshmikanthan S, Zieba BJ, Ge ZD, Momotani K, Zheng X, Lund H, Artamonov MV, Maas JE, Szabo A, Zhang DX, Auchampach JA, Mattson DL, Somlyo AV, Chrzanowska-Wodnicka M. Lakshmikanthan S, et al. Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1486-94. doi: 10.1161/ATVBAHA.114.303678. Epub 2014 May 1. Arterioscler Thromb Vasc Biol. 2014. PMID: 24790136 Free PMC article.